The pathophysiology of uterine adenomyosis: An update

The article outlines current understanding of the etiology of adenomyosis and the role of the myometrium, and outlines how MRI and transvaginal ultrasound have enhanced our understanding of the disease.

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Authors

Giuseppe Benagiano, Ph.D., M.D., Marwan Habiba, Ph.D., F.R.C.O.G., Ivo Brosens, Ph.D., M.D.

Vol 98, Issue 3, Pages 572-579

Abstract

The diagnosis of adenomyosis using noninvasive techniques such as vaginal ultrasounds and magnetic resonance has clear clinical applications and has renewed the interest in the pathogenesis of uterine adenomyosis. However, the research remains hampered by the lack of consensus on the classification of lesions. Magnetic resonance imaging and transvaginal ultrasound have comparable diagnostic accuracy. Minimal interventional biopsy techniques have recently been introduced. This article reviews human and animal studies and provides an update on the pathophysiology of adenomyosis. Recent views on the pathogenesis and links with endometriosis are discussed.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)00697-8/fulltext


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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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