February 2019

Volume 111, Issue 2

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Introduction: Stimulate the mitochondria! A Bonington approach to improving assisted reproductive technology outcomes or a call to action?
Richard S. Legro
Vol 111 | No. 2 | February 2019 | Pages 195–196

Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging
Emre Seli, Tianren Wang, Tamas L. Horvath
Vol 111 | No. 2 | February 2019 | Pages 197–204

Mitochondrial DNA copy number as a predictor of embryo viability
Gustavo N. Cecchino, Juan A. Garcia-Velasco
Vol 111 | No. 2 | February 2019 | Pages 205–211

Metabolic imaging via fluorescence lifetime imaging microscopy for egg and embryo assessment
Tim Sanchez, Man Zhang, Dan Needleman, Emre Seli
Vol 111 | No. 2 | February 2019 | Pages 212–218

Mitochondria as a tool for oocyte rejuvenation
Elena Labarta, Maria José de los Santos, Maria José Escribá, Antonio Pellicer, Sonia Herraiz
Vol 111 | No. 2 | February 2019 | Pages 219–226

Fertile battle

To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context?
Carlos Simon
Vol 111 | No. 2 | February 2019 | Pages 227–228

Should the reproductive risk of a couple aiming to conceive be tested in the contemporary clinical context?
Antonio Capalbo, Davit Chokoshvili, Lorraine Dugoff, Jason Franasiak, Norbert Gleicher, Guido Pennings, Carlos Simon
Vol 111 | No. 2 | February 2019 | Pages 229–238

Inklings

Evidence-based medicine when the evidence is poor
Mark Sigman
Vol 111 | No. 2 | February 2019 | Page 239

Seminal contribution

Vilaprisan in women with uterine fibroids: the randomized phase 2b ASTEROID 1 study
Linda D. Bradley, Sukhbir S. Singh, James Simon, Kristina Gemzell-Danielsson, Kathrin Petersdorf, Esther Groettrup-Wolfers, Xiaowei Ren, Michal Zvolanek, Christian Seitz
Vol 111 | No. 2 | February 2019 | Pages 240–248

Reflections

Vilaprisan phase 2B trial: a timely efficacy and safety study of a novel selective progesterone receptor modulator for nonsurgical management of uterine fibroids
Julia L. Magnay
Vol 111 | No. 2 | February 2019 | Pages 249–250

Is it time to start folate supplementation in men? The effect of paternal folate status on embryonic growth
Philip J. Cheng, Alexander W. Pastuszak, James M. Hotaling
Vol 111 | No. 2 | February 2019 | Pages 251–252

Demystifying “mosaic” outcomes
Eric J. Forman
Vol 111 | No. 2 | February 2019 | Page 253

Tipping the scales for reproduction: a weighty problem
Samuel J. Chantilis
Vol 111 | No. 2 | February 2019 | Pages 254–255

Opportunities and challenges for population-based studies investigating the effects of air pollution on pregnancy loss
Sandie Ha, Pauline Mendola
Vol 111 | No. 2 | February 2019 | Pages 256–257

Optimizing the opportunity for female fertility preservation in a limited time-frame for patients with cancer using in vitro maturation and ovarian tissue cryopreservation
Roger J. Hart
Vol 111 | No. 2 | February 2019 | Pages 258–259

Adjusting for age: is it enough to just say you did it?
George Patounakis, Micah J. Hill
Vol 111 | No. 2 | February 2019 | Pages 260–261

Future fertility in survivors of childhood cancer—examining the impact of cancer treatment on uterus function
Kenny A. Rodriguez-Wallberg, Jan I. Olofsson
Vol 111 | No. 2 | February 2019 | Pages 262–263

Is antimüllerian hormone an early marker or an in utero effector of incipient polycystic ovary syndrome?
Ricardo Azziz
Vol 111 | No. 2 | February 2019 | Pages 264–265

Early phenotypes in polycystic ovary syndrome: some answers, more questions
Laura C. Torchen
Vol 111 | No. 2 | February 2019 | Pages 266–267

Vitamin D, a promising natural compound with anti-uterine fibroid characteristics
Mohamed Ali, Ayman Al-Hendy, Qiwei Yang
Vol 111 | No. 2 | February 2019 | Pages 268–269

Andrology

Does the father matter? The association between the periconceptional paternal folate status and embryonic growth
Jeffrey Hoek, Maria P.H. Koster, Sam Schoenmakers, Sten P. Willemsen, Anton H.J. Koning, Eric A.P. Steegers, Régine P.M. Steegers-Theunissen
Vol 111 | No. 2 | February 2019 | Pages 270–279

Assisted reproduction

One hundred mosaic embryos transferred prospectively in a single clinic: exploring when and why they result in healthy pregnancies
Andrea R. Victor, Jack C. Tyndall, Alan J. Brake, Laura T. Lepkowsky, Alex E. Murphy, Darren K. Griffin, Rajiv C. McCoy, Frank L. Barnes, Christo G. Zouves, Manuel Viotti
Vol 111 | No. 2 | February 2019 | Pages 280–293

Effect of class III and class IV obesity on oocyte retrieval complications and outcomes
Phillip A. Romanski, Leslie V. Farland, Lawrence C. Tsen, Elizabeth S. Ginsburg, Erin I. Lewis
Vol 111 | No. 2 | February 2019 | Pages 294–301.e1

Risk factors for monozygotic twinning after in vitro fertilization: a systematic review and meta-analysis
Andrea Busnelli, Chiara Dallagiovanna, Marco Reschini, Alessio Paffoni, Luigi Fedele, Edgardo Somigliana
Vol 111 | No. 2 | February 2019 | Pages 302–317

Prediction of implantation after blastocyst transfer in in vitro fertilization: a machine-learning perspective
Celine Blank, Rogier Rudolf Wildeboer, Ilse DeCroo, Kelly Tilleman, Basiel Weyers, Petra de Sutter, Massimo Mischi, Benedictus Christiaan Schoot
Vol 111 | No. 2 | February 2019 | Pages 318–326

Endometriosis

Pathogenesis of endometriosis: the genetic/epigenetic theory
Philippe R. Koninckx, Anastasia Ussia, Leila Adamyan, Arnaud Wattiez, Victor Gomel, Dan C. Martin
Vol 111 | No. 2 | February 2019 | Pages 327–340

Environment

Acute effects of air pollutants on spontaneous pregnancy loss: a case-crossover study
Claire L. Leiser, Heidi A. Hanson, Kara Sawyer, Jacob Steenblik, Ragheed Al-Dulaimi, Troy Madsen, Karen Gibbins, James M. Hotaling, Yetunde Oluseye Ibrahim, James A. VanDerslice, Matthew Fuller
Vol 111 | No. 2 | February 2019 | Pages 341–347

Epidemiology

Assisted conception does not increase the risk for mother-to-child transmission of hepatitis B virus, compared with natural conception: a prospective cohort study
Rui Nie, Mingyue Wang, Tantan Liao, Kun Qian, Guijin Zhu, Lei Jin
Vol 111 | No. 2 | February 2019 | Pages 348–356

Fertility preservation

Serum antimüllerian hormone is associated with the number of oocytes matured in vitro and with primordial follicle density in candidates for fertility preservation
Nathalie Sermondade, Charlotte Sonigo, Christophe Sifer, Sophie Valtat, Marianne Ziol, Florence Eustache, Michaël Grynberg
Vol 111 | No. 2 | February 2019 | Pages 357–362

BRCA carriers have similar reproductive potential at baseline to noncarriers: comparisons in cancer and cancer-free cohorts undergoing fertility preservation
Vinay Gunnala, Jessica Fields, Mohamad Irani, Debra D'Angelo, Kangpu Xu, Glenn Schattman, Zev Rosenwaks
Vol 111 | No. 2 | February 2019 | Pages 363–371

Gynecology

Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors
Laurence E.X.M. van de Loo, Marleen H. van den Berg, Annelies Overbeek, Marloes van Dijk, Layla Damen, Cornelis B. Lambalk, Cécile M. Ronckers, Marry M. van den Heuvel-Eibrink, Leontien C.M. Kremer, Helena J. van der Pal, Joop S.E. Laven, Wim J.E. Tissing, Jacqueline J. Loonen, Birgitta Versluys, Dorine Bresters, Gerardus J.L. Kaspers, Flora E. van Leeuwen, Eline van Dulmen-den Broeder on behalf of the DCOG LATER-VEVO Study Group
Vol 111 | No. 2 | February 2019 | Pages 372–380

Reproductive endocrinology

Higher luteinizing hormone levels associated with antimüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome
Nicolás Crisosto, Amanda Ladrón de Guevara, Bárbara Echiburú, Manuel Maliqueo, Gabriel Cavada, Ethel Codner, Francisco Paez, Teresa Sir-Petermann
Vol 111 | No. 2 | February 2019 | Pages 381–388

Minimal difference in phenotype between adolescents and young adults with polycystic ovary syndrome
Temeka Zore, Daria Lizneva, Soumia Brakta, Walidah Walker, Larisa Suturina, Ricardo Azziz
Vol 111 | No. 2 | February 2019 | Pages 389–396

Reproductive science

Inhibition of tumor cell proliferation in human uterine leiomyomas by vitamin D via Wnt/β-catenin pathway
Ana Corachán, Hortensia Ferrero, Alejandra Aguilar, Nuria Garcia, Javier Monleon, Amparo Faus, Irene Cervelló, Antonio Pellicer
Vol 111 | No. 2 | February 2019 | Pages 397–407

Video

Laparoscopic ovarian tissue harvesting and orthotopic ovarian cortex grafting for fertility preservation: less is more
Anne Fortin, Henri Azaïs, Catherine Uzan, Gilles Lefebvre, Geoffroy Canlorbe, Catherine Poirot
Vol 111 | No. 2 | February 2019 | Pages 408–410

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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