Endometritis, new time, new concepts
Article In Press
Kotaro Kitaya, M.D., Takumi Takeuchi, M.D., Shimpei Mizuta, M.Sc., Hidehiko Matsubayashi, M.D., Tomomoto Ishikawa, M.D.
Endometritis is subdivided into two categories. Acute endometritis is symptomatic and characterized by microabscess formation and neutrophil invasion in the endometrial superficial epithelium, gland lumina, and uterine cavity. Chronic endometritis is rather silent and recognized as unusual plasmacyte infiltration in the endometrial stromal areas. Over the last decade, studies have disclosed the potential association between poor reproductive outcomes and endometritis, particularly chronic endometritis. The aim of this review is to address the current literature surrounding chronic endometritis and highlight recent advances in the research of this long-neglected gynecologic disease.