Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine
  • American Society for Reproductive Medicine
  • United States of America

Low-molecular-weight heparins induce decidual heparin-binding epidermal growth factor–like growth factor expression and promote survival of decidual cells undergoing apoptosis

The effects of tinzaparin and enoxaparin on decidual cells were evaluated. Tinzaparin induced heparinbinding epidermal growth factor–like growth factor expression and secretion. Both low-molecular-weight heparins prevented tumor necrosis factor (TNF) a–induced apoptosis of decidual cells.