Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine
  • American Society for Reproductive Medicine
  • United States of America

Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes

Plasminogen is present in the oviductal fluid. Plasminogen and plasminogen activators are present in oolemma and zona pellucida of matured oocytes. After IVF, the immunoreactivity for plasminogen and its activators in oocytes decreases. Presence of plasminogen in the IVF medium decreases polyspermy rates.

Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled trial

We studied the effect of acupuncture and exercise on hemostatic factors, insulin sensitivity, and adipose tissue characteristics in PCOS. Acupuncture counteracted a possible prothrombotic state in women with PCOS as reflected by decreased plasminogen activator inhibitor activity.