Cross-talk between miR-29c and transforming growth factor-β3 is mediated by an epigenetic mechanism in leiomyoma
There is a cross-talk between TGF-b3 and miR-29c in leiomyoma wherein TGF-b3 inhibits the expression of miR-29c through an epigenetic mechanism involving DNMT1.
Effect of body mass index on pregnancy outcomes with the freeze-all strategy in women with polycystic ovarian syndrome
An elevated body mass index has a statistically inverse association with the live birth rate in women with polycystic ovary syndrome with the freeze- all strategy.
Symptoms of anxiety and depression among Chinese women transitioning through menopause: findings from a prospective community-based cohort study
This prospective study of peri- and postmenopausal Chinese women found depressive symptoms more prevalent than anxiety symptoms and mood problems perhaps increased during the menopausal transition and early postmenopausal stage.
Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study
Ulipristal acetate (UPA) stimulates the autophagic response in primary cultured leiomyoma cells, whereas in matched myometrial cells autophagy remains un- changed after UPA treatment.
Long-term follow-up after successful Essure sterilization: evaluation of patient satisfaction, symptoms, and the influence of negative publicity
After a 144-month follow-up of Essure sterilization, 49.5% of women reported symptoms and 16.1% underwent removal surgery. Negative publicity had an influence on patients’ decision regarding Essure removal surgery.
Population-level assessment using demographic analyses and multivariate regression reveals statistically significant differentiation in the likelihood of assisted reproduction technology births by sociodemographic groups, suggesting potential unmet need and hidden demand.
Fertility treatments and offspring pediatric infectious morbidities: results of a population-based cohort with a median follow-up of 10 years
Fertility treatments are associated with increased risk for offspring infectious morbidities in a large population based cohort with a follow-up of up to 18 years.
Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease
RNA-seq analyses showed that M1 macrophages are more proinflammatory in the eutopic endometrium of women with endometriosis than in control endometrium and that M2 macrophages paradoxically display a proinflammatory phenotype in disease.
Levels of angiogenic markers in second-trimester maternal serum from in vitro fertilization pregnancies with oocyte donation
Angiogenic markers are not altered in in vitro fertilization pregnancy with oocyte donation despite unique secretion patterns for other second-trimester hormones, such as alpha-fetoprotein and inhibin A, in these cases.
Endometrial CD138 count appears to be a negative prognostic indicator for patients who have experienced previous embryo transfer failure
Endometrial CD138 count may predict the outcome of frozen embryo transfer in patients who have previously failed the transfer of two high-quality fresh embryos.
Impact of maternal prepregnancy body mass index on cognitive and metabolic profiles of singletons born after in vitro fertilization/intracytoplasmic sperm injection
Maternal prepregnancy obesity and overweight is associated with increased risks for obesity, overweight, and intellectual disability at early age of offspring conceived through in vitro fertilization/intracytoplasmic inject.
Time of morulation and trophectoderm quality are predictors of a live birth after euploid blastocyst transfer: a multicenter study
Time of morulation and trophectoderm quality are statistically significantly associated with euploid blastocyst reproductive competence, as shown across three in vitro fertilization centers using similar culture conditions.