Juvenile cystic adenomyoma, a rare diagnostic challenge: Case Reports and literature review

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VOLUME 2, ISSUE 2, P166-171, JUNE 01, 2021


Sushila Arya, M.D., M.S., Heather R. Burks, M.D.



To report 2 very rare cases of young women who presented with severe dysmenorrhea and a large cystic lesion in the myometrium, which presented a diagnostic dilemma because they were confused with a Müllerian anomaly.


Case reports and a literature review.


A university-based reproductive endocrinology and infertility clinic in the United States.


An 18- and a 16-year-old nulliparous girl presented with worsening of their longstanding pelvic pain, and imaging study results were suggestive of a Müllerian anomaly.


Abdominal and pelvic computed tomography, transvaginal ultrasonography, pelvic magnetic resonance imaging, operative laparoscopy, and excision of a juvenile cystic adenomyoma (JCA).

Main Outcome Measure(s)

Resolution of the pelvic pain and restoration of normal uterine anatomy after appropriate intervention


Restoration of normal uterine anatomy, which was confirmed by 3-dimensional ultrasonography for case 1; however, case 2 still had a small remnant of JCA postoperatively.


Clinical and radiologic examinations may not be useful in differentiating a Müllerian anomaly from other rare abnormalities like JCA. When in doubt, laparoscopy can assist in diagnosing and treating the condition.

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