Are we approaching automated assisted reproductive technology? Embryo culture, metabolomics, and cryopreservation

Review Article

VOLUME 2, ISSUE 4, P251-264, OCTOBER 01, 2021

Authors:

Valentina Casciani, Ph.D., Daniela Galliano, M.D., Ph.D., Jason M. Franasiak, M.D., Giulia Mariani, M.D., Marcos Meseguer, Ph.D.

Abstract:

For decades, assisted reproductive technology (ART) procedures have been performed manually thanks to the meticulous work of skilled embryologists. Recently, new technologies have been developed with three main scopes: improving embryo culture conditions; making diagnostic evaluations more consistent and reliable; and allowing ART procedures to become progressively less subjective and operator-dependent. This review aimed to answer the following questions: is automation likely to be successfully incorporated into the in vitro fertilization laboratory and clinical ART in the future? If so, would such automation result in improved outcomes in ART?