Time to revisit the adage: relax and you will get pregnant
50 Years Ago Today
VOLUME 116, ISSUE 3, P695
Eve C. Feinberg, M.D., Jessica Tozour, M.D.
“What is now proved was once only imagined”– William Blake
The September 1971 issue of Fertility and Sterility contains the article “The contractile response of the human uterus, fallopian tubes, and ovary to prostaglandins in vivo” by Countinho and Maia (1). This was the first study to evaluate the in vivo effects of prostaglandin F2 (PGF2) and prostaglandin E2 (PGE2) on the ovary, uterus, and fallopian tube. A recording device to monitor contractility was placed into the fallopian tube lumen of eight subjects and into the fibromuscular tissue of the ovarian stroma. Uterine activity was recorded by an intrauterine balloon. Either PGE2, PGF2, or both were infused and contractility was recorded.