Techniques for successful vaginal anastomosis in the uterine transplantation patient

Guidelines for preparing recipient vagina and donorto-recipient vaginal anastomosis at the time of uterine transplantation.

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VOLUME 115, ISSUE 3, P802-803, MARCH 01, 2021

Authors:

Jenna M. Rehmer, M.D., Cecile A. Ferrando, M.D., Rebecca Flyckt, M.D., Tommaso Falcone, M.D.

Abstract:

Objective

To demonstrate techniques for successful donor-to-recipient vaginal anastomosis in uterine transplantation including illustration of a tension-free technique.

Design

This video uses live-action footage from surgery, detailed animations, and illustrations to review the step-by-step technique we use for vaginal anastomosis in uterine transplantation. Institutional Review Board approval was obtained for this experimental surgery.

Setting

Academic medical center.

Patient(s)

Patients undergoing uterine transplantation.

Intervention(s)

Preparation of recipient vagina with illustration of challenges and risk secondary to dense adhesions between bladder and neo-vagina. Use of surgical techniques. Key steps include appropriate preparation of both donor and recipient vaginal tissues and a tension-free closure with horizontal mattress stitches.

Main Outcome Measure(s)

Intraoperative techniques in the clinical research trial of uterine transplantation.

Results

Successful vaginal anastomosis in the uterine transplantation patient.

Conclusion(s)

This video provides a step-by-step guide to vaginal anastomosis in uterine transplantation patients. Our team has applied techniques from vaginal reconstructive surgery in an attempt to reduce the occurrence of postoperative vaginal strictures, with attention to planned donor and recipient anastomosis site tissue preparation and closure of the anastomosis using a tension-free suturing technique.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.