September 2021

Volume 116, Issue 3

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Views and Reviews

Iatrogenic male infertility: medical and surgical treatments that impair male fertility
Mark Sigman
Vol 116 | No. 3 | September 2021 | Pages 609-610

The role of benign prostatic hyperplasia treatments in ejaculatory dysfunction
Priyanka Bearelly, Gabriella Juliet Avellino
Vol 116 | No. 3 | September 2021 | Pages 611-617 

Medical therapies causing iatrogenic male infertility
Danielle Velez, Samuel Ohlander
Vol 116 | No. 3 | September 2021 | Pages 618-624 

Iatrogenic effects of radical cancer surgery on male fertility
Zhenyue Huang, William T. Berg
Vol 116 | No. 3 | September 2021 | Pages 625-629 

Inklings 

Oscillations of estradiol and gonadotropins are a missing link to solving the mystery of mono-ovulation in humans
Dmitri I. Dozortsev, Antonio Pellicer, Michael P. Diamond
Vol 116 | No. 3 | September 2021 | Pages 630-632

Seminal Contributions

Intramuscular progesterone optimizes live birth from programmed frozen embryo transfer: a randomized clinical trial
Kate Devine, Kevin S. Richter, Samad Jahandideh, Eric A. Widra, Jeffrey L. McKeeby
Vol 116 | No. 3 | September 2021 | Pages 633-643

ASRM Pages

Ethical issues in oocyte banking for nonautologous use: an Ethics Committee opinion
Ethics Committee of the American Society for Reproductive Medicine
Vol 116 | No. 3 | September 2021 | Pages 644-650

Guidance on the limits to the number of embryos to transfer: a committee opinion
Practice Committee of the American Society for Reproductive Medicine and the Practice Committee for the Society for Assisted Reproductive Technologies
Vol 116 | No. 3 | September 2021 | Pages 651-654 

Reflections

Not throwing away my shot but taking less: three-arm randomized controlled trial finds equivalent live birth rate with intramuscular progesterone every third day for programmed frozen embryo transfer cycles
Leah Hawkins Bressler, Jennifer E. Mersereau
Vol 116 | No. 3 | September 2021 | Pages 655-656 

What is the role of varicocelectomy in infertile men with clinical varicoceles and elevated sperm DNA fragmentation?
Shirley L. Wang, Bronwyn S. Bedrick, Taylor P. Kohn
Vol 116 | No. 3 | September 2021 | Pages 657-658 

Birth weight may affect male long-term reproductive fitness
Andrea Borini, Giovanni Coticchio
Vol 116 | No. 3 | September 2021 | Page 659

COVID-19 infection in pregnancy: a Spanish perspective of spontaneous and in vitro fertilization pregnancies
Jacqueline C. Lee, Jennifer F. Kawwass
Vol 116 | No. 3 | September 2021 | Pages 660-661 

Dreaming up fertility treatment coverage and musing on simple and meaningful assisted reproductive technology metrics: the global assisted reproductive technology report by the International Committee for Monitoring Assisted Reproductive Technologies
Paul Pirtea, Dominique de Ziegler, James P. Toner
Vol 116 | No. 3 | September 2021 | Pages 662-663 

Ovarian stimulation protocols: Don’t immediately change a losing team
Alexander M. Quaas
Vol 116 | No. 3 | September 2021 | Pages 664-665

“Quality is not an act, it is a habit.” Reflection on the role of the fertilization rate in the quality control strategies of assisted reproduction treatments
Ángeles Valera, Marcos Meseguer
Vol 116 | No. 3 | September 2021 | Pages 666-667 

Variant haplophasing by long-read sequencing: proof of concept in preimplantation genetic workup and an opportunity to distinguish balanced and normal embryos
Cheri Margolis, Marie Werner, Chaim Jalas
Vol 116 | No. 3 | September 2021 | Pages 668-669 

Perinatal outcome of assisted reproductive technology: Is stillbirth of significant importance?
Mona Aboulghar, Mohamed Aboulghar
Vol 116 | No. 3 | September 2021 | Pages 670-671 

Kisspeptin, a promising biomarker for miscarriage in early pregnancy
Rong Li, Kai-Lun Hu
Vol 116 | No. 3 | September 2021 | Pages 672-673 

Medication management in the 21st century: There should be an app for that!
Eduardo Hariton
Vol 116 | No. 3 | September 2021 | Pages 674-675 

Is in vitro fertilization an indication for fetal echocardiography?
Efstratios Kolibianakis, Themistoklis I. Dagklis
Vol 116 | No. 3 | September 2021 | Pages 676-677

Running the Red Queen’s race—investigating environmental phenols as potential contributors to preterm birth
Michael S. Bloom, Roy Gerona, Victor Y. Fujimoto
Vol 116 | No. 3 | September 2021 | Pages 678-679 

Lending clarity via specificity to the diagnosis of chronic endometritis
Nola S. Herlihy, Jason M. Franasiak
Vol 116 | No. 3 | September 2021 | Pages 680-681 

Potential later-life health implications of polycystic ovary syndrome are underserved and understudied
Bart C.J.M. Fauser
Vol 116 | No. 3 | September 2021 | Pages 682-683 

The coronavirus era elephant in the room: What do we do about fellowship interviews?
Audrey S. Garneau, Leah Hawkins Bressler
Vol 116 | No. 3 | September 2021 | Pages 684-685 

Reproductive medicine at the crossroads of stem cell biology and big-data
Jonathan L. Tilly, Dori C. Woods
Vol 116 | No. 3 | September 2021 | Pages 686-687 

One size does not fit all: a nuanced approach to surgical management of interstitial ectopic pregnancy
Meghan McGrattan, Ally Murji
Vol 116 | No. 3 | September 2021 | Pages 688-690 

Enhanced myometrial vascularity—the time has come for individualized treatment of focal uterine pathology
Meghan O’Leary, Ari P. Sanders
Vol 116 | No. 3 | September 2021 | Pages 691-692 

The septate uterus and metroplasty—another dogma under siege
Mark P. Trolice
Vol 116 | No. 3 | September 2021 | Pages 693-694

Fertility and Sterility: 50 Years Ago Today

Time to revisit the adage: relax and you will get pregnant
Eve C. Feinberg, Jessica Tozour
Vol 116 | No. 3 | September 2021 | Page 695

Original Articles

Andrology 

Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis
Filipe Tenório Lira Neto, Matheus Roque, Sandro C. Esteves
Vol 116 | No. 3 | September 2021 | Pages 696-712 

Z-scores for comparative analyses of spermatogonial numbers throughout human development
Miriam Funke, Yifan Yang, Atte Lahtinen, Klara Benninghoven-Frey, Sabine Kliesch, Nina Neuhaus, Jan-Bernd Stukenborg, Kirsi Jahnukainen
Vol 116 | No. 3 | September 2021 | Pages 713-720 

Men born small for gestational age or with low birth weight do not improve their rate of reproduction over time: a Swedish population-based study
Susanne Liffner, Marie Bladh, Elizabeth Nedstrand, Mats Hammar, Heriberto Rodriguez Martinez, Gunilla Sydsjö
Vol 116 | No. 3 | September 2021 | Pages 721-730

Assisted Reproduction

Perinatal outcomes of pregnancies resulting from assisted reproduction technology in SARS-CoV-2-infected women: a prospective observational study
Virginia Engels Calvo, Sara Cruz Melguizo, Alejandra Abascal-Saiz, Laura Forcén Acebal, Amalia Sánchez-Migallón, Pilar Pintado Recarte, Celia Cuenca Marín, Beatriz Marcos Puig, Pablo G. Del Barrio Fernández, Olga Nieto Velasco, María Luisa de la Cruz Conty, Oscar Martínez-Perezon behalf of the Spanish Obstetric Emergency Group
Vol 116 | No. 3 | September 2021 | Pages 731-740 

International Committee for Monitoring Assisted Reproductive Technologies (ICMART): world report on assisted reproductive technologies, 2013
Manish Banker, Silke Dyer, Georgina M. Chambers, Osamu Ishihara, Markus Kupka, Jacques de Mouzon, Fernando Zegers-Hochschild, G. David Adamson
Vol 116 | No. 3 | September 2021 | Pages 741-756 

Changing stimulation protocol on repeat conventional ovarian stimulation cycles does not lead to improved laboratory outcomes
Kaitlyn Wald, Eduardo Hariton, Jerrine R. Morris, Ethan A. Chi, Eleni G. Jaswa, Marcelle I. Cedars, Charles E. McCulloch, Mitchell Rosen
Vol 116 | No. 3 | September 2021 | Pages 757-765

Fertilization rate as a novel indicator for cumulative live birth rate: a multicenter retrospective cohort study of 9,394 complete in vitro fertilization cycles
Giulia Scaravelli, Carlotta Zacà, Paolo Emanuele Levi Setti, Claudia Livi, Filippo Maria Ubaldi, Maria Teresa Villani, Ermanno Greco, Maria Elisabetta Coccia, Alberto Revelli, Giuseppe Ricci, Francesco Fusi, Vincenzo Vigiliano, Roberto De Luca, Simone Bolli, Andrea Borini
Vol 116 | No. 3 | September 2021 | Pages 766-773 

Variant haplophasing by long-read sequencing: a new approach to preimplantation genetic testing workups
Yanfei Cheng M.M, Qian Yu, Minyue Ma, Hui Wang, Shuang Tian, Wenling Zhang, Jinning Zhang Yifan Liu, Qi Yang, Xiao Pan, Hongbin Liang, Li Wang, Don Leigh, David S. Cram, Yuanqing Yao
Vol 116 | No. 3 | September 2021 | Pages 774-783

Assisted reproductive technologies and the risk of stillbirth in singleton pregnancies: a systematic review and meta-analysis
Karoline Gundersen Sarmon, Troels Eliasen, Ulla Breth Knudsen, Bjørn Bay
Vol 116 | No. 3 | September 2021 | Pages 784-792 

A randomized controlled trial to evaluate the use of a web-based application to manage medications during in vitro fertilization
Caitlin Elizabeth Martin, Michael Lanham, Alison Almgren-Bell, Courtney Marsh, Kenan Omurtag
Vol 116 | No. 3 | September 2021 | Pages 793-800 

Early Pregnancy

Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization
Kurt R. Bjorkman, Sarah H. Bjorkman, Dina J. Ferdman, Anna K. Sfakianaki, Joshua A. Copel, Mert Ozan Bahtiyar
Vol 116 | No. 3 | September 2021 | Pages 801-808 

Performance of plasma kisspeptin as a biomarker for miscarriage improves with gestational age during the first trimester
Ali Abbara, Maya Al-Memar, Maria Phylactou, Christopher Kyriacou, Pei Chia Eng, Rans Nadir, Chioma Izzi-Engbeaya, Sophie A. Clarke, Edouard G. Mills, Elisabeth Daniels, Lechun Huo, Ewa Pacuszka, Lisa Yang, Bijal Patel, Tricia Tan, Paul Bech, Alexander N. Comninos, Hanine Fourie, Tom W. Kelsey, Tom Bourne, Waljit S. Dhillo
Vol 116 | No. 3 | September 2021 | Pages 809-819 

Environment 

Prenatal urinary concentrations of phenols and risk of preterm birth: exploring windows of vulnerability
Yu Zhang, Vicente Mustieles, Paige L. Williams, Jennifer Yland, Irene Souter, Joseph M. Braun, Antonia M. Calafat, Russ Hauser, Carmen Messerlian
Vol 116 | No. 3 | September 2021 | Pages 820-832

Epidemiology

A North American prospective study of depression, psychotropic medication use, and semen quality
Jennifer J. Yland, Michael L. Eisenberg, Elizabeth E. Hatch, Kenneth J. Rothman, Craig J. McKinnon, Yael I. Nillni, Greg J. Sommer, Tanran R. Wang, Lauren A. Wise
Vol 116 | No. 3 | September 2021 | Pages 833-842 

Genetics

Identifying susceptibility genes for primary ovarian insufficiency on the high-risk genetic background of a fragile X premutation
Cristina E. Trevino, J. Christopher Rounds, Krista Charen, Lisa Shubeck, Heather S. Hipp, Jessica B. Spencer, H. Richard Johnston, Dave J. Cutler, Michael E. Zwick, Michael P. Epstein, Anna Murray, James N. Macpherson, Montserrat Mila, Laia Rodriguez-Revenga, Elizabeth Berry-Kravis, Deborah A. Hall, Maureen A. Leehey, Ying Liu, Corrine Welt, Stephen T. Warren, Stephanie L. Sherman, Peng Jin, Emily G. Allen
Vol 116 | No. 3 | September 2021 | Pages 843-854

Gynecology

Redefining chronic endometritis: the importance of endometrial stromal changes
Dana B. McQueen, Kruti P. Maniar, Anne Hutchinson, Rafael Confino, Lia Bernardi, Mary Ellen Pavone
Vol 116 | No. 3 | September 2021 | Pages 855-861 

Reproductive Endocrinology 

Higher risk of type 2 diabetes in women with hyperandrogenic polycystic ovary syndrome
Sofia Persson, Evangelia Elenis, Sahruh Turkmen, Michael S. Kramer, Eu-Leong Yong, Inger Sundström Poromaa
Vol 116 | No. 3 | September 2021 | Pages 862-871

Perceptions and lessons from web-based interviews for the reproductive endocrinology and infertility fellowship application cycle
Eduardo Hariton, Christina A. Raker, Gary N. Frishman, Eve C. Feinberg
Vol 116 | No. 3 | September 2021 | Pages 872-881

Reproductive Science 

The endometrial response to modulation of ligand-progesterone receptor pathways is reversible
Rohan R. Chodankar, Alison Murray, Moira Nicol, Lucy H.R. Whitaker, Alistair R.W. Williams, Hilary O.D. Critchley
Vol 116 | No. 3 | September 2021 | Pages 882-895 

Pathways and factors regulated by bone marrow-derived stem cells in human ovarian tissue
Anna Buigues, Patricia Diaz-Gimeno, Patricia Sebastian-Leon, Livia Pellegrini, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz
Vol 116 | No. 3 | September 2021 | Pages 896-908

Videos

Hysteroscopy-assisted laparoscopic salpingectomy for interstitial pregnancy without cornual resection
Ceana Nezhat, Youssef Youssef, Andrew A. Toledo
Vol 116 | No. 3 | September 2021 | Pages 909-911 

Enhanced myometrial vascularity: case presentation and review
Jeffrey Woo, Bruce Kahn
Vol 116 | No. 3 | September 2021 | Pages 912-914 

Three degrees of separation: complete uterine and cervical septa
Colleen M. Miller, Chandra C. Shenoy, Zaraq Khan
Vol 116 | No. 3 | September 2021 | Pages 915-916 

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.