Secondary azoospermia after sleeve gastrectomy: a case report

Case Report

Like Comment
Related Content

VOLUME 2, ISSUE 2, P245-248, JUNE 01, 2021


Gricelda Gomez, M.D., M.P.H., Alexandra Berger, M.D., Martin Kathrins, M.D. 



To report the first case of secondary azoospermia after sleeve gastrectomy.


Case report.


Academic male infertility clinic.


A 33-year-old man with secondary azoospermia and primary testicular failure with testosterone deficiency after laparoscopic sleeve gastrectomy.


Hormonal therapy with anastrozole for 10 months and diagnostic testicular biopsy.

Main Outcome Measure(s)

Semen analyses and testicular histopathology.


Non-obstructive azoospermia persisted at 20 months after surgery despite hormonal therapy with anastrozole. Testicular histopathology revealed the presence of Sertoli cells only.


Although further research is need to determine the relationship between sleeve gastrectomy and secondary infertility, men should be informed of the potentially deleterious effects of this surgery on semen parameters.

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.