Outlining the practical options for coping with the shortcomings of vaginal progesterone recently unveiled in frozen embryo transfers: a story drafted in Turkey
Article In Press
Dominique de Ziegler, M.D., Paul Pirtea, M.D., Jean-Marc Ayoubi, M.D., Ph.D.
Recently our attention has been once again focused on progesterone, which we had erroneously believed to operate on a simple binary “on-off” mode. Indeed, converging reports now indicate that serum concentrations of progesterone are important, while we had believed that solely uterine concentrations counted. Thus, it is time to revisit our concepts on the role of progesterone, notably in early pregnancy after frozen embryo transfers (FETs) conducted using hormone replacement therapy (HRT).