November 2021

Volume 116, Issue 5

Like Comment

Views and Reviews

Planting the seed of doubt: the diagnosis and management of mosaic embryos
Eve C. Feinberg
Vol 116 | No. 5 | November 2021 | Pages 1203-1204

The “mosaic” embryo: misconceptions and misinterpretations in preimplantation genetic testing for aneuploidy
Nathan R. Treff, Diego Marin
Vol 116 | No. 5 | November 2021 | Pages 1205-1211

Let the data do the talking: the need to consider mosaicism during embryo selection
Manuel Viotti, Rajiv C. McCoy, Darren K. Griffin, Francesca Spinella, Ermanno Greco, Mitko Madjunkov, Svetlana Madjunkova, Clifford L. Librach, Andrea R. Victor, Frank L. Barnes, Christo G. Zouves
Vol 116 | No. 5 | November 2021 | Pages 1212-1219

Evidence-based management of preimplantation chromosomal mosaicism: lessons from the clinic
Andria G. Besser, Emily L. Mounts, James A. Grifo
Vol 116 | No. 5 | November 2021 | Pages 1220-1224

Inklings 

After the deluge or never after the deluge
Richard S. Legro
Vol 116 | No. 5 | November 2021 | Pages 1225-1226

Seminal Contributions

A machine learning algorithm can optimize the day of trigger to improve in vitro fertilization outcomes
Eduardo Hariton, Ethan A. Chi, Gordon Chi, Jerrine R. Morris, Jon Braatz, Pranav Rajpurkar, Mitchell Rosen
Vol 116 | No. 5 | November 2021 | Pages 1227-1235

Reflections: The ghost in the machine (learning)
Leah M. Roberts, Thomas A. Molinaro
Vol 116 | No. 5 | November 2021 | Pages 1236-1237

ASRM Pages

ASRM müllerian anomalies classification 2021
Samantha M. Pfeifer, Marjan Attaran, Jessica Goldstein, Steven R. Lindheim, John C. Petrozza, Beth W. Rackow, Evan Siegelman, Robert Troiano, Thomas Winter, Andrea Zuckerman, Sarah D. Ramaiah
Vol 116 | No. 5 | November 2021 | Pages 1238-1252 

Reflections: The new ASRM müllerian anomaly classification: a picture is worth one thousand words
Ann J. Davis, Richard H. Reindollar
Vol 116 | No. 5 | November 2021 | Pages 1253-1254

Fertility evaluation of infertile women: a committee opinion
Practice Committee of the American Society for Reproductive Medicine
Vol 116 | No. 5 | November 2021 | Pages 1255-1265

Obesity and reproduction: a committee opinion
Practice Committee of the American Society for Reproductive Medicine
Vol 116 | No. 5 | November 2021 | Pages 1266-1285 

Fertility and Sterility: 50 Years Ago Today

Let’s get the lead out!
Olivia Carpinello, Alan DeCherney
Vol 116 | No. 5 | November 2021 | Page 1286 

Original Articles

Andrology

One size does not fit all: variations by ethnicity in demographic characteristics of men seeking fertility treatment across North America
Andrew B. Chen, Keith A. Jarvi, Katherine Lajkosz, James F. Smith, Kirk C. Lo, Ethan D. Grober, Susan Lau, Jared M. Bieniek, Robert E. Brannigan, Victor D.W. Chow, Trustin Domes, James M. Dupree, Marc Goldstein, Jason C. Hedges, James M. Hotaling, Edmund Y. Ko, Peter N. Kolettis, Ajay K. Nangia, Jay I. Sandlow, David Shin, Aaron Spitz, J.C. Trussell, Scott I. Zeitlin, Armand S. Zini, Marc A. Fisher, Thomas J. Walsh, Tung-Chin M. Hsieh, Eugene F. Fuchs, Mary K. Samplaski
Vol 116 | No. 5 | November 2021 | Pages 1287-1294

Reflections: Racial differences in men seeking fertility treatment in North America: a timely report by the Andrology Research Consortium
Bobby B. Najari
Vol 116 | No. 5 | November 2021 | Pages 1295-1296

Deoxyribonucleic acid methylation signatures in sperm deoxyribonucleic acid fragmentation
Weijian Zhu, Lei Jiang, Chengshuang Pan, Junhui Sun, Xuefeng Huang, Wuhua Ni
Vol 116 | No. 5 | November 2021 | Pages 1297-1307

Quantitative selection of single human sperm with high DNA integrity for intracytoplasmic sperm injection
Zhuoran Zhang, Changsheng Dai, Guanqiao Shan, Xin Chen, Hang Liu, Khaled Abdalla, Iryna Kuznyetsova, Sergey Moskovstev, Xi Huang, Clifford Librach, Keith Jarvi, Yu Sun
Vol 116 | No. 5 | November 2021 | Pages 1308-1318

Can we select human sperm with high DNA integrity for intracytoplasmic sperm injection on the basis of motility and morphology?
Kajal Khodamoradi, Emad Ibrahim, Ranjith Ramasamy
Vol 116 | No. 5 | November 2021 | Page 1319

Assisted Reproduction

A new definition of recurrent implantation failure on the basis of anticipated blastocyst aneuploidy rates across female age
Baris Ata, Erkan Kalafat, Edgardo Somigliana
Vol 116 | No. 5 | November 2021 | Pages 1320-1327 

Reflections: Recurrent implantation failure—It’s time to get personal
Alex Polyakov, Wan-Tinn Teh, Genia Rozen
Vol 116 | No. 5 | November 2021 | Pages 1328-1329

Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: part II, donor oocyte cycles
Jianjun Hu, Emanuela Molinari, Sarah K. Darmon, Lin Zhang, Pasquale Patrizio, David H. Barad, Norbert Gleicher
Vol 116 | No. 5 | November 2021 | Pages 1330-1340 

Early Pregnancy

Mean differences in maternal body mass index and recurrent pregnancy loss: a systematic review and meta-analysis of observational studies
Abey Eapen, Emily T. Hayes, Dana B. McQueen, Molly Beestrum, Patrick Ten Eyck, Christina Boots
Vol 116 | No. 5 | November 2021 | Pages 1341-1348

Reflections: How much weight do we put into body mass index as a factor in recurrent pregnancy loss? Body mass index and recurrent pregnancy loss, a weighty topic
Pamela B. Parker, Wes Urian, Sacha A. Krieg
Vol 116 | No. 5 | November 2021 | Pages 1349-1350

Genetics

Embryonic lethal genetic variants and chromosomally normal pregnancy loss
Jennie Kline, Badri Vardarajan, Avinash Abhyankar, Sonja Kytömaa, Bruce Levin, Nara Sobreira, Andrew Tang, Amanda Thomas-Wilson, Ruiwei Zhang, Vaidehi Jobanputra
Vol 116 | No. 5 | November 2021 | Pages 1351-1358

Reflections: Getting to the point (mutation)
Sinem Karipcin, Shan Wei, Zev Williams
Vol 116 | No. 5 | November 2021 | Page 1359

Renal agenesis-related genes are associated with Herlyn-Werner-Wunderlich syndrome
Lin Li, Chunfang Chu, Shenghui Li, Dan Lu, Ping Zheng, Jie Sheng, Li-Jing Luo, Xia Wu, Yu-Di Zhang, Chenghong Yin, Ai-hong Duan
Vol 116 | No. 5 | November 2021 | Pages 1360-1369

Renal agenesis, associated genital malformations, and responsible genes
Pedro Acién, Maribel Acién
Vol 116 | No. 5 | November 2021 | Pages 1370-1371

Infertility

Development and validation of a risk prediction index for severe maternal morbidity based on preconception comorbidities among infertile patients
Gayathree Murugappan, Ruben J. Alvero, Deirdre J. Lyell, Abha Khandelwal, Stephanie A. Leonard
Vol 116 | No. 5 | November 2021 | Pages 1372-1380

Innovations in infertility: a comprehensive analysis of the ClinicalTrials.gov database
Benjamin J. Peipert, Daniel Spinosa, Elizabeth P. Howell, Jeremy M. Weber, Tracy Truong, Benjamin S. Harris
Vol 116 | No. 5 | November 2021 | Pages 1381-1390

Reproductive Science

Podocalyxin inhibits human embryo implantation in vitro and luminal podocalyxin in putative receptive endometrium is associated with implantation failure in fertility treatment
Sophea Heng, Nirukshi Samarajeewa, Asma Aberkane, Wafaa Essahib, Hilde Van de Velde, Maxine Scelwyn, M. Louise Hull, Beverley Vollenhoven, Luk J. Rombauts, Guiying Nie
Vol 116 | No. 5 | November 2021 | Pages 1391-1401

Reflections: Molecular Teflon and fertility: an old adhesion regulator takes center stage
Kelly M. McNagny, Michael R. Hughes, Julyanne Brassard
Vol 116 | No. 5 | November 2021 | Pages 1402-1403

Extracellular matrix remodeling and inflammatory pathway in human endometrium: insights from uterine leiomyomas
Laura Governini, Camilla Marrocco, Bianca Semplici, Valentina Pavone, Giuseppe Belmonte, Stefano Luisi, Felice Petraglia, Alice Luddi, Paola Piomboni
Vol 116 | No. 5 | November 2021 | Pages 1404-1414

Stuck in the middle with you(terus): another look at the impact of intramural leiomyomas on the endometrium
Edward B. Nguyen, Lusine Aghajanova
Vol 116 | No. 5 | November 2021 | Pages 1415-1416

Videos

Conservative cesarean scar pregnancy treatment: local methotrexate injection followed by hysteroscopic removal with hysteroscopic tissue removal system
Paolo Casadio, Marco Ambrosio, Ludovica Verrelli, Paolo Salucci, Alessandro Arena, Renato Seracchioli
Vol 116 | No. 5 | November 2021 | Pages 1417-1419

A case of neovagina surgical creation using the uterine cervix remnant in a patient with Mayer-Rokitansky-Küster-Hauser syndrome
Mykhailo Medvediev, Dmytro Spesyvtsev, Dar'ya Pokrovenko
Vol 116 | No. 5 | November 2021 | Pages 1420-1422

Hysteroscopic incision of the incomplete uterine septum using 5-French scissors with marking strategies: a modified hysteroscopic technique
Waixing Li, Bingsi Gao, Zhenkun Guan, Xingping Zhao, Huan Huang, Aiqian Zhang, Grace Johnson, Jeffrey Woo, Chunxia Cheng, Xiaoming Guan, Dabao Xu
Vol 116 | No. 5 | November 2021 | Pages 1423-1425

Reflections: Hysteroscopic septoplasty: many techniques, little evidence
Shirin Dason, Siddhi Mathur, Ally Murji
Vol 116 | No. 5 | November 2021 | Pages 1426-1427

 

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.