June 2020

Volume 113, Issue 6

Views and reviews

Introduction: How evident is the evidence?
Carlos Simon
Vol 113 | No. 6 | June 2020 | Pages 1091–1092

Large randomized controlled trials in infertility
Rui Wang, Zi-Jiang Chen, Lan N. Vuong, Richard S. Legro, Ben W. Mol, Jack Wilkinson
Vol 113 | No. 6 | June 2020 | Pages 1093–1099

Coordination and planning of clinical research on a national and global level
Adam J. Devall, Henk Jan Out, Ben Willem J. Mol, James M.N. Duffy, Barbara Collura, Silke Dyer
Vol 113 | No. 6 | June 2020 | Pages 1100–1106

Methodologic considerations in randomized clinical trials in reproductive medicine
Christos Venetis, Thomas d’Hooghe, Kurt T. Barnhart, Patrick M.M. Bossuyt, Ben Willem J. Mol
Vol 113 | No. 6 | June 2020 | Pages 1107–1112

Integrity of randomized controlled trials: challenges and solutions
Wentao Li, Madelon van Wely, Lyle Gurrin, Ben W. Mol
Vol 113 | No. 6 | June 2020 | Pages 1113–1119

Fertile battle

Empiric and lifestyle therapies for male infertility—should we recommend them?
Mark Sigman
Vol 113 | No. 6 | June 2020 | Page 1120

Should empiric therapies be used for male factor infertility?
Kai J. Buhling, Peter Chan, Martin Kathrins, Marian Showell, Sarah C. Vij, Mark Sigman
Vol 113 | No. 6 | June 2020 | Pages 1121–1130


Deep inside the pandemic, from inactivity to action: let’s be ready
Marcos Meseguer, Craig Niederberger, Antonio Pellicer
Vol 113 | No. 6 | June 2020 | Pages 1131–1132

E-cigarette use in reproductive-aged women and pregnancy: a rising health concern
Shruti Agarwal, Mark P. Trolice, Steven R. Lindheim
Vol 113 | No. 6 | June 2020 | Pages 1133–1134

Seminal contributions

No evidence of severe acute respiratory syndrome–coronavirus 2 in semen of males recovering from coronavirus disease 2019
Feng Pan, Xingyuan Xiao, Jingtao Guo, Yarong Song, Honggang Li, Darshan P. Patel, Adam M. Spivak, Joseph P. Alukal, Xiaoping Zhang, Chengliang Xiong, Philip S. Li, James M. Hotaling
Vol 113 | No. 6 | June 2020 | Pages 1135–1139

ASRM pages

Prior and novel coronaviruses, Coronavirus Disease 2019 (COVID-19), and human reproduction: what is known?
James Segars, Quinton Katler, Dana B. McQueen, Alexander Kotlyar, Tanya Glenn, Zac Knight, Eve C. Feinberg, Hugh S. Taylor, James P. Toner, Jennifer F. Kawwass for the American Society for Reproductive Medicine Coronavirus/COVID-19 Task Force
Vol 113 | No. 6 | June 2020 | Pages 1140–1149

Repetitive oocyte donation: a committee opinion
Practice Committee of the American Society for Reproductive Medicine and Practice Committee of the Society for Assisted Reproductive Technology
Vol 113 | No. 6 | June 2020 | Pages 1150–1153


Coronavirus disease 2019 and men’s reproductive health
Michael L. Eisenberg
Vol 113 | No. 6 | June 2020 | Page 1154

Failing to mature: somatic cell dysfunction in the spermatogenic niche among patients with Sertoli cell–only and Klinefelter syndromes
Davide Pietro Cinà, Ryan Flannigan
Vol 113 | No. 6 | June 2020 | Pages 1155–1156

In search of a new biomarker to predict poor ovarian response
Eric J. Forman
Vol 113 | No. 6 | June 2020 | Page 1157

Diagnosing endometriosis by measuring plasma micro ribonucleic acids: it may take a miRacle
Joshua R. Friedman, Caleb B. Kallen
Vol 113 | No. 6 | June 2020 | Pages 1158–1159

Do children conceived using in vitro fertilization have poorer elementary school outcomes than children conceived spontaneously?
Russell S. Kirby
Vol 113 | No. 6 | June 2020 | Page 1160

Is a naturally reduced antimüllerian hormone at a young age linked to an increased risk of cancer development?
Human M. Fatemi, Barbara Lawrenz
Vol 113 | No. 6 | June 2020 | Pages 1161–1162

Bioinformatic jujutsu to defeat an endometrial transcriptomic foe
Steven L. Young
Vol 113 | No. 6 | June 2020 | Pages 1163–1164

Does a compromised placenta contribute to transgenerational transmission of metabolic dysfunction in polycystic ovary syndrome?
David H. Abbott
Vol 113 | No. 6 | June 2020 | Pages 1165–1166

Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!
Mohamed Ali, Sahar Esfandyari, Ayman Al-Hendy
Vol 113 | No. 6 | June 2020 | Pages 1167–1168

Surgery for rectal endometriosis: the technique or the indication, that is the question
Paolo Vercellini, Greta Sergenti, Edgardo Somigliana
Vol 113 | No. 6 | June 2020 | Pages 1169–1170

The solution to endometriosis isn’t always in vitro fertilization
Preston Parry
Vol 113 | No. 6 | June 2020 | Page 1171

Tuboplasty, thank-you notes, and the revival of lost arts
Courtney L. Birchall, Stephanie J. Estes
Vol 113 | No. 6 | June 2020 | Pages 1172–1173


Semen infections in men with primary infertility in the real-life setting
Luca Boeri, Filippo Pederzoli, Paolo Capogrosso, Costantino Abbate, Massimo Alfano, Nicasio Mancini, Massimo Clementi, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
Vol 113 | No. 6 | June 2020 | Pages 1174–1182

Characterization of the stem cell niche components within the seminiferous tubules in testicular biopsies of Klinefelter patients
Dorien Van Saen, Veerle Vloeberghs, Inge Gies, Jean De Schepper, Herman Tournaye, Ellen Goossens
Vol 113 | No. 6 | June 2020 | Pages 1183–1195.e3

The role of total chromosomal disomy in human spermatozoa as a predictor of the outcome of pre-implantation genetic screening
Suhua Jiang, Xiangjie Peng, Fei Gong, Chuan Huang, Yangqin Peng, Xingyu Long, Ge Lin, Wenbing Zhu
Vol 113 | No. 6 | June 2020 | Pages 1196–1204.e1

Assisted reproduction

Cycle day 2 insulin-like growth factor-1 serum levels as a prognostic tool to predict controlled ovarian hyperstimulation outcomes in poor responders
Limor Man, Jovana Lekovich, Chelsea Canon, Zev Rosenwaks, Daylon James
Vol 113 | No. 6 | June 2020 | Pages 1205–1214

Effect of paternal body mass index on neonatal outcomes of singletons after frozen−thawed embryo transfer cycles: analysis of 7,908 singleton newborns
Meng Ma, Wei Zhang, Jie Zhang, Zhou Liang, Yanping Kuang, Yun Wang
Vol 113 | No. 6 | June 2020 | Pages 1215–1223.e1


Estrogen receptor-α immunoreactivity predicts symptom severity and pain recurrence in deep endometriosis
Nicola Pluchino, Ramanaiah Mamillapalli, Jean-Marie Wenger, Lauriane Ramyead, Panagiotis Drakopoulos, Jean-Christophe Tille, Hugh S. Taylor
Vol 113 | No. 6 | June 2020 | Pages 1224–1231.e1 

Identification of candidate microRNA markers of endometriosis with the use of next-generation sequencing and quantitative real-time polymerase chain reaction
Elahe Papari, Mehrdad Noruzinia, Ladan Kashani, Warren G. Foster
Vol 113 | No. 6 | June 2020 | Pages 1232–1241


Third grade academic achievement among children conceived with the use of in vitro fertilization: a population-based study in Texas
Barbara Luke, Morton B. Brown, Mary K. Ethen, Mark A. Canfield, Stephanie Watkins, Ethan Wantman, Kevin J. Doody
Vol 113 | No. 6 | June 2020 | Pages 1242–1250.e4

Fertility preservation

Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency
Kutluk H. Oktay, Giuliano Bedoschi, Shari B. Goldfarb, Enes Taylan, Shiny Titus, Glenn E. Palomaki, Tessa Cigler, Mark Robson, Maura N. Dickler
Vol 113 | No. 6 | June 2020 | Pages 1251–1260.e1


Uterine disorders affecting female fertility: what are the molecular functions altered in endometrium?
Almudena Devesa-Peiro, Patricia Sebastian-Leon, Francisco Garcia-Garcia, Vicente Arnau, Alejandro Aleman, Antonio Pellicer, Patricia Diaz-Gimeno
Vol 113 | No. 6 | June 2020 | Pages 1261–1274

Reproductive endocrinology

Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome
Miao Sun, Bo Sun, Shicong Qiao, Xiaoling Feng, Yan Li, Shuwen Zhang, Yuhan Lin, Lihui Hou
Vol 113 | No. 6 | June 2020 | Pages 1275–1285.e2

Metagenomic analysis identified microbiome alterations and pathological association between intestinal microbiota and polycystic ovary syndrome
Weiwei Chu, Qixin Han, Jieying Xu, Juan Wang, Yun Sun, Weiping Li, Zi-Jiang Chen, Yanzhi Du
Vol 113 | No. 6 | June 2020 | Pages 1286–1298.e4

Left ventricular myocardial mass index and its correlates as an early marker of cardiovascular risk among nonobese normotensive Indian women with polycystic ovary syndrome: lessons from a cross-sectional study
Aafia Rashid, Akbar Masood, Ishfaq A. Wani, Imran Hafeez, Tabasum Parvez, Mohd Afzal Zagar, Mohd Ashraf Ganie
Vol 113 | No. 6 | June 2020 | Pages 1299–1307.e2 

Reproductive science

Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells
Tsai-Der Chuang, Amit Rehan, Omid Khorram
Vol 113 | No. 6 | June 2020 | Pages 1308–1318 

Reproductive surgery 

Outcome after surgery for deep endometriosis infiltrating the rectum
Celine Bafort, Barbara van Elst, Sofie Neutens, Christel Meuleman, Annouschka Laenen, André d’Hoore, Albert Wolthuis, Carla Tomassetti
Vol 113 | No. 6 | June 2020 | Pages 1319–1327.e3


Use of a shaving technique for surgical management of partial ureteral obstruction due to endometriosis
Pavan K. Ananth, Leigh A. Humphries, Ceana H. Nezhat
Vol 113 | No. 6 | June 2020 | Pages 1328–1329

Laparoscopic tuboplasty for mild distal tubal disease
Sarah Norris, Charlotte Axelrod, Mara Sobel, Crystal Chan
Vol 113 | No. 6 | June 2020 | Pages 1330–1332