February 2021: What should the first-line treatment for couples with unexplained infertility be in Latin America? (Spanish-Language Event)

Journal Club Global

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Club Global Académico: ¿Cual debe de ser la primera línea de tratamiento en parejas con infertilidad inexplicable en Latino-América?

Nuestro debate se enfocará en el manejo óptimo de la infertilidad inexplicable, y como el problema debe de ser abordado en Latinoamérica basado en la literatura global reciente.

La infertilidad inexplicable es vista entre 15% y 30% de las parejas que acuden a una clínica de fertilidad. La inseminación intrauterina (IIU) es ampliamente utilizada como una alternativa de tratamiento de bajo costo, y menos invasiva que la fertilización in Vitro (FIV) para parejas con infertilidad inexplicable. Sin embargo, en algunos países se considera que después de 2 años de manejo expectativo, FIV es el tratamiento a seguir, y no IIU con o sin inducción de la ovulación.

¿Esta estrategia es posible en Latinoamérica? ¿Deberían las pacientes recibir tres o cuatro IIU o un ciclo de FIV? ¿Debería el costo o acceso a servicios ser una consideración? Estas importantes preguntas serán debatidas por expertos en Medicina Reproductiva de varios países Latinoamericanos en nuestro primer Club Global académico en español.

What Should the First-Line Treatment for Couples with Unexplained Infertility be in Latin America?

Our debate will focus on the optimal approach to treat unexplained infertility, and how this needs to be addressed in Latin America based on the current literature.

Unexplained infertility is seen in 15% to 30% of couples who attend fertility clinics. Intrauterine insemination (IUI) is widely used as a low-cost, less-invasive alternative to in vitro fertilization (IVF) for couples with unexplained infertility. However, some countries consider that after two years of expectant management, IVF is the treatment of choice.

Is this approach feasible in Latin America? Should patients receive three or four cycles of IUI or one cycle of IVF? Should cost or access to care be a consideration? These key questions will be debated by reproductive medicine experts from different Latin American countries in our first Spanish Journal Club Global.


J. Ricardo Loret de Mola, MD, Host
Dr. J. Ricardo Loret de Mola is Professor and Chairman, Department of Obstetrics and Gynecology and Professor of Microbiology, Immunology and Cell Biology at Southern Illinois University. He serves as Gynecologist-in-Chief and Medical Director for Women's Services HSHS St. Johns Hospital in Springfield, Illinois.

Guido de Jesus Parra Anaya, MD, Colombia 
Dr. Parra Anaya is an Obstetrician-Gynecologist and Reproductive Medicine Specialist. He is a founder of the Instituto de Reproducción Humana Procrear from the city of Barranquilla-Colombia, current Secretary of ALMER from 2020-2022, and Past President of ALMER-ACCER & FECOLSOG.

Carlos Salazar, MD, Mexico 
Dr. Salazar is the Chairman of the Assisted Reproductive Unit of the Hospital, Staff of the Obstetrics and Gynecology Department, and Professor of Human Reproductive Biology Residence Program of the Hospital UNAM.

Dr. Sergio Papier, MD, Argentina
Dr. Papier is a reproductive medicine specialist, Medical Director of CEGYR, and President of the Executive Council of ALMER.

Alejandro Manzur-Yanine, MD, Chile
Dr. Manzur-Yanine is President of the Chilean Society of Reproductive Medicine (SOCMER), Associate Professor of Medicine at University Finis Terrae, Ex-President of ALMER, and practices in the Reproductive Medicine Unit at Monteblanco Clinic.

Ricardo Pommer, MD, Chile
Dr. Pommer is the Medical Director at Monteblanco Clinic, President of the Chilean Society of Obstetrics and Gynecology, and President of the Chilean Society of Reproductive Medicine.

Victor Alfonso Batiza Resendiz, MD, Mexico
Dr. Batiza is Mexican board-certified in OB-GYN and Reproductive Biology and is Vice President of the Mexican Association of Reproductive Medicine.

Kurt Barnhart, MD, MSCE
Dr. Barnhart is the Video and New Media Editor at Fertility and Sterility. He is the William Shippen, Jr. Professor of Obstetrics and Gynecology at The Perelman School of Medicine at the University of Pennsylvania.

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.