Views and Reviews

Legal considerations in reproductive medicine
Susan L. Crockin, William D. Schlaff
Vol 115 | No. 2 | February 2021 | Pages 261-262 

Physician autonomy or discrimination: the risks and limits of saying “no”
Judith Daar
Vol 115 | No. 2 | February 2021 | Pages 263-267

Addressing legal issues in cross-border gestational surrogacy: current topics and trends
Margaret E. Swain, Colin James Rogerson
Vol 115 | No. 2 | February 2021 | Pages 268-273

Storage, transport, and disposition of gametes and embryos: legal issues and practical considerations
Lisa A. Rinehart
Vol 115 | No. 2 | February 2021 | Pages 274-281

Legal challenges in reproductive genetics
Sonia M. Suter
Vol 115 | No. 2 | February 2021 | Pages 282-289

Business law issues for assisted reproductive technology practices and practitioners: considerations for sales or mergers of fertility practices
Richard M. Yanofsky, Theodore F. Hanselman
Vol 115 | No. 2 | February 2021 | Pages 290-295

Inklings

Reproductive medicine, as seen through single-cell glasses
Felipe Vilella, Carlos Simon
Vol 115 | No. 2 | February 2021 | Pages 296-297

ASRM Pages

In vitro maturation: a committee opinion
Practice Committees of the American Society for Reproductive Medicine, the Society of Reproductive Biologists and Technologists, and the Society for Assisted Reproductive Technology
Vol 115 | No. 2 | February 2021 | Pages 298-304

A review of best practices of rapid-cooling vitrification for oocytes and embryos: a committee opinion
Practice Committees of the American Society for Reproductive Medicine and Society of Reproductive Biologists and Technologists
Vol 115 | No. 2 | February 2021 | Pages 305-310

Reflections

Understanding sperm motility regulation: it’s a long road ahead
Ettore Caroppo
Vol 115 | No. 2 | February 2021 | Pages 311-312 

Seeking the elusive genes associated with varicocele: a step forward
Viviane P. Santana, Sandro C. Esteves
Vol 115 | No. 2 | February 2021 | Pages 313-314

Nonobstructive azoospermia: a spectrum, not a single disease
Michael B. Tradewell, Thomas A. Masterson
Vol 115 | No. 2 | February 2021 | Page 315

Euploidy prediction: possible or impossible? Closer or further away?
Marcos Meseguer
Vol 115 | No. 2 | February 2021 | Page 316

Emerging therapies for endometriosis
Hugh S. Taylor
Vol 115 | No. 2 | February 2021 | Pages 317-318

My mama had endometriosis
William E. Gibbons
Vol 115 | No. 2 | February 2021 | Pages 319-320

Effects of endometriosis on assisted reproductive technology: gone with the wind
Paul Pirtea, Dominique de Ziegler, Jean Marc Ayoubi
Vol 115 | No. 2 | February 2021 | Pages 321-322

An oncofertility prediction tool? Forecasting fertility after cancer
Paula C. Brady, Eric J. Forman
Vol 115 | No. 2 | February 2021 | Pages 323-324

Antimüllerian hormone and spontaneous preterm birth: more research is needed before we can change clinical guidelines
Inger Sundström Poromaa
Vol 115 | No. 2 | February 2021 | Page 325

Polycystic ovary syndrome and preterm birth—what’s going on?
Sonia L. Robinson, Edwina H. Yeung
Vol 115 | No. 2 | February 2021 | Pages 326-327

Expanding our knowledge of premature ovarian insufficiency
Robert W. Rebar, Christopher S. Keator
Vol 115 | No. 2 | February 2021 | Pages 328-329

Is in vitro fertilization the answer in polycystic ovary syndrome?
Sajal Gupta, Annika Sinha
Vol 115 | No. 2 | February 2021 | Pages 330-331

Sexual dysfunction in polycystic ovary syndrome: a complex entity that may find improvement with the simplest of solutions
Heather G. Huddleston
Vol 115 | No. 2 | February 2021 | Pages 332-333 

The heart of the matter: balancing potential cardiovascular risks with known benefits of gender-affirming testosterone
Daphna Stroumsa, Amanda R. Schwartz, Molly B. Moravek
Vol 115 | No. 2 | February 2021 | Pages 334-335

Umbilical cord blood–derived platelet-rich plasma: a clinically acceptable substitute for fetal bovine serum?
Cristina Subiran, Stine Gry Kristensen, Claus Yding Andersen
Vol 115 | No. 2 | February 2021 | Pages 336-337

Transforming growth factor β–sphingosine 1-phosphate axis in pathogenesis of endometriosis
Sahar Houshdaran, Camran Nezhat
Vol 115 | No. 2 | February 2021 | Pages 338-339

Vitamin D and uterine leiomyomata: Is it time to let the sunshine in?
Vaishnavi Purusothaman, Steven L. Young
Vol 115 | No. 2 | February 2021 | Pages 340-341 

Improving access to procreative care through affordable hysteroscopic myomectomy
Preston Parry
Vol 115 | No. 2 | February 2021 | Page 342

Mayer-Rokitansky-Küster-Hauser syndrome associated with fused renal ectopia and hydroureter
Samantha M. Pfeifer
Vol 115 | No. 2 | February 2021 | Pages 343-344

Delving deep into excision of bowel endometriosis
Adela G. Cope, Zaraq Khan
Vol 115 | No. 2 | February 2021 | Pages 345-346

Fertility and Sterility: 50 Years Ago Today

Promises and pitfalls of male contraceptive vaccines
Jennifer B. Bakkensen, Eve C. Feinberg
Vol 115 | No. 2 | February 2021 | Pages 347

Original Articles

Andrology 

Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility
Joana Vieira Silva, Maria João Freitas, Joana Santiago, Sarah Jones, Sofia Guimarães, Srinivasan Vijayaraghavan, Steven Publicover, Giorgio Colombo, John Howl, Margarida Fardilha
Vol 115 | No. 2 | February 2021 | Pages 348-362 

Molecular characteristics of varicocele: integration of whole-exome and transcriptome sequencing
Bo Yang,Yuan Yang, Yunqiang Liu, Hong Li, Shangqing Ren, Zhufeng Peng, Kun Fang, Luchen Yang, Qiang Dong
Vol 115 | No. 2 | February 2021 | Pages 363-372 

Predictive model to estimate the chances of successful sperm retrieval by testicular sperm aspiration in patients with nonobstructive azoospermia
Ahmad Majzoub, Mohamed Arafa, Kareim Khalafalla, Sami AlSaid, Hasan Burjaq, Moza Albader, Thoraya Al-Marzooqi, Sandro C. Esteves, Haitham Elbardisi
Vol 115 | No. 2 | February 2021 | Pages 373-381

Assisted Reproduction

Can embryo morphokinetic parameters predict euploid pregnancy loss?
Dana B. McQueen, Jenna Mazur, Dana Kimelman, Rafael Confino, Jared C. Robins, Lia A. Bernardi, Chen Yeh, John Zhang, Mary Ellen Pavone
Vol 115 | No. 2 | February 2021 | Pages 382-388

Early Pregnancy

Serum ferritin level is inversely related to number of previous pregnancy losses in women with recurrent pregnancy loss
Maja Georgsen, Maria Christine Krog, Anne-Sofie Korsholm, Helene Westring Hvidman, Astrid Marie Kolte, Andreas Stribolt Rigas, Henrik Ullum, Søren Ziebe, Anders Nyboe Andersen, Henriette Svarre Nielsen, Morten Bagge Hansen
Vol 115 | No. 2 | February 2021 | Pages 389-396

Endometriosis 

Relugolix, an oral gonadotropin-releasing hormone receptor antagonist, reduces endometriosis-associated pain in a dose–response manner: a randomized, double-blind, placebo-controlled study
Yutaka Osuga, Yoshifumi Seki, Masataka Tanimoto, Takeru Kusumoto, Kentarou Kudou, Naoki Terakawa
Vol 115 | No. 2 | February 2021 | Pages 397-405

Pregnancy and delivery outcomes in women with rectovaginal endometriosis treated either conservatively or operatively
Anni Tuominen, Liisu Saavalainen, Aila Tiitinen, Oskari Heikinheimo, Päivi Härkki
Vol 115 | No. 2 | February 2021 | Pages 406-415

Endometriosis does not impact live-birth rates in frozen embryo transfers of euploid blastocysts
Lauren A. Bishop, Justin Gunn, Samad Jahandideh, Kate Devine, Alan H. Decherney, Micah J. Hill
Vol 115 | No. 2 | February 2021 | Pages 416-422

Responsiveness and thresholds for clinically meaningful changes in worst pain numerical rating scale for dysmenorrhea and nonmenstrual pelvic pain in women with moderate to severe endometriosis
Robin M. Pokrzywinski, Ahmed M. Soliman, Michael C. Snabes, Jun Chen, Hugh S. Taylor, Karin S. Coyne
Vol 115 | No. 2 | February 2021 | Pages 423-430

Fertility Preservation 

A predictive model for chemotherapy-related diminished ovarian reserve in reproductive-age women
Margaret M. Hopeman, Katherine E. Cameron, Maureen Prewitt, Kurt Barnhart, Jill P. Ginsberg, Mary D. Sammel, Clarisa R. Gracia
Vol 115 | No. 2 | February 2021 | Pages 431-437

Infertility

Highly elevated level of antimüllerian hormone associated with preterm delivery in polycystic ovary syndrome patients who underwent ovulation induction
Amy Kaing, Eleni A. Jaswa, Michael P. Diamond, Richard S. Legro, Marcelle I. Cedars, Heather G. Huddleston
Vol 115 | No. 2 | February 2021 | Pages 438-446 

Reproductive Endocrinology

Neonatal outcomes in women with polycystic ovary syndrome after frozen-thawed embryo transfer
Jiaying Lin, Haiyan Guo, Bian Wang, Qiuju Chen, Qianqian Zhu
Vol 115 | No. 2 | February 2021 | Pages 447-454

New theca-cell marker insulin-like factor 3 is associated with premature ovarian insufficiency
Chendi Zhu, Wei Luo, Zhuqing Li, Xiruo Zhang, Jingmei Hu, Shidou Zhao, Xue Jiao, Yingying Qin
Vol 115 | No. 2 | February 2021 | Pages 455-462

Different expression and localization of aquaporin 7 and aquaporin 9 in granulosa cells, oocytes, and embryos of patients with polycystic ovary syndrome and the negatively correlated relationship with insulin regulation
Wen-Yan Song, Yuan Wang, Xiao-Man Hou, Cheng-Cheng Tian, Liang Wu, Xue-Shan Ma, Hai-Xia Jin, Gui-Dong Yao, Ying-Pu Sun
Vol 115 | No. 2 | February 2021 | Pages 463-473

Lifestyle modifications alone or combined with hormonal contraceptives improve sexual dysfunction in women with polycystic ovary syndrome
Marissa Steinberg Weiss, Andrea Hsu Roe, Kelly C. Allison, William C. Dodson, Penny M. Kris-Etherton, Allen R. Kunselman, Christy M. Stetter, Nancy I. Williams, Carol L. Gnatuk, Stepanie J. Estes, David B. Sarwer, Christos Coutifaris, Richard S. Legro, Anuja Dokras
Vol 115 | No. 2 | February 2021 | Pages 474-482

Testosterone administration increases leukocyte-endothelium interactions and inflammation in transgender men
Francesca Iannantuoni, Juan Diego Salazar, Aranzazu Martinez de Marañon, Celia Bañuls, Sandra López-Domènech, Milagros Rocha, Felipe Hurtado-Murillo, Carlos Morillas, Marcelino Gómez-Balaguer, Víctor Manuel Víctor
Vol 115 | No. 2 | February 2021 | Pages 483-489

Reproductive Science

Comparison of different sources of platelet-rich plasma as treatment option for infertility-causing endometrial pathologies
Lucía de Miguel–Gómez, Sara López-Martínez, Hannes Campo, Emilio Francés-Herrero, Amparo Faus, Ana Díaz, Antonio Pellicer, Francisco Domínguez, Irene Cervelló
Vol 115 | No. 2 | February 2021 | Pages 490-500

Sphingosine 1-phosphate receptors are dysregulated in endometriosis: possible implication in transforming growth factor β–induced fibrosis
Caterina Bernacchioni, Tommaso Capezzuoli, Valentina Vannuzzi, Francesca Malentacchi, Francesca Castiglione, Francesca Cencetti, Marcello Ceccaroni, Chiara Donati, Paola Bruni, Felice Petraglia
Vol 115 | No. 2 | February 2021 | Pages 501-511

Vitamin D as an effective treatment in human uterine leiomyomas independent of mediator complex subunit 12 mutation
Ana Corachán, María Gabriela Trejo, María Cristina Carbajo-García, Javier Monleón, Julia Escrig, Amparo Faus, Antonio Pellicer, Irene Cervelló, Hortensia Ferrero
Vol 115 | No. 2 | February 2021 | Pages 512-521

Videos

Hysteroscopic myomectomy for submucosal type 2 fibroids with cold enucleation technique and complete fibroid extraction using a double-lumen intracervical cannula
Walter Osorio, Natalia Posada, John Cano, Sergio Tamayo, Juan Giraldo
Vol 115 | No. 2 | February 2021 | Pages 522-524

Mayer-Rokitansky-Küster-Hauser syndrome with rare findings of inferior crossed-fused renal ectopia and Gartner's duct cyst: a video case report
Guiling Liang, Wei Xia, Yan Liang, Qian Zhu, Lujia Zou, Jian Zhang, Haowen Jiang
Vol 115 | No. 2 | February 2021 | Pages 525-527

Laparoscopic single-stapler technique in rectosigmoid resection in women with deep infiltrating endometriosis
Jiri Hanacek, Lukas Havluj, Noble Ayayee, Iva Urbánková, Jan Drahonovsky
Vol 115 | No. 2 | February 2021 | Pages 528-530