F&S Science: August 2020

Volume 1, Issue 1

From the Editor-in-Chief 

From the Editor-in-Chief
William H. Catherino
Vol 1 | No. 1 | August 2020 | Pages 1–2


Serendipity in the search for “morning-after pills” led to clomiphene for the induction of ovulation
Craig Jordan
Vol 1 | No. 1 | August 2020 | Pages 3–13

Looking into the Crystal Ball

Polygenic risk scoring in the human embryo: reproductive genetics, final frontier?
Nathan R. Treff
Vol 1 | No. 1 | August 2020 | Pages 14–15

Original Articles

Gamete Biology

Decreased gremlin 1 expression in women with body mass index ≥35 kg/m2 is mediated by interleukin 10 and interleukin 1β in the follicular fluid
Tana Kim, Yohan Kim, Fabrice Lucien, Yulian Zhao, Elizabeth Ann L. Enninga
Vol 1 | No. 1 | August 2020 | Pages 16–26

Neurotensin stimulates the sperm acrosome reaction and reduces percentages of fertilization in vitro
Genevieve E. Campbell, Estella L. Jones, Pierre Comizzoli, Diane M. Duffy
Vol 1 | No. 1 | August 2020 | Pages 27–35

Mitochondrial DNA content decreases during in vitro human embryo development: insights into mitochondrial DNA variation in preimplantation embryos donated for research
Marta Pérez-Sánchez, Antonio Díez-Juan, Diana Beltrán, Amparo Mifsud, Amparo Mercader, Carmina Vidal, Elena Labarta, Antonio Pellicer, Emre Seli, María José De Los Santos
Vol 1 | No. 1 | August 2020 | Pages 36–45

Short-acting testosterone appears to have lesser effect on male reproductive potential compared with long-acting testosterone in mice
Kevin Y. Chu, Shathiyah Kulandavelu, Thomas A. Masterson, Emad Ibrahim, Himanshu Arora, Ranjith Ramasamy
Vol 1 | No. 1 | August 2020 | Pages 46–52

Embryo and Endometrial Assessment

Photoacoustic laser effects in live mouse blastocysts: pilot safety studies of DNA damage from photoacoustic imaging doses
Erin Newcomer, Guang Yang, Bei Sun, Hongbo Luo, Duanwen Shen, Samuel Achilefu, Valerie Ratts, Joan Riley, John Yeh, Quing Zhu
Vol 1 | No. 1 | August 2020 | Pages 53–58

Genome-wide estrogen receptor-α binding and action in human endometrial stromal cells
Bahar D. Yilmaz, Christia A.M. Sison, Sule Yildiz, Kaoru Miyazaki, John Coon V, Ping Yin, Serdar E. Bulun
Vol 1 | No. 1 | August 2020 | Pages 59–66

Uterine Gpr83 mRNA is highly expressed during early pregnancy and GPR83 mediates the actions of PEN in endometrial and non-endometrial cells
Nataliya Parobchak, Shivani Rao, Ariel Negron, Jennifer Schaefer, Moshmi Bhattacharya, Sally Radovick, Andy V. Babwah
Vol 1 | No. 1 | August 2020 | Pages 67–77

Reproductive Diseases

Characterization of the role of Activator Protein 1 signaling pathway on extracellular matrix deposition in uterine leiomyoma
Justin Pilgrim, Jacquel Arismendi, Anthony DeAngelis, Terrence Lewis, Joy Britten, Minnie Malik, William H. Catherino
Vol 1 | No. 1 | August 2020 | Pages 78–89

Increased CXCL12 expression in endometrium of women with abnormal uterine bleeding is post-transcriptionally mediated via miR-23b-3p and is associated with decreased expression of the miR-23b-3p/24-3p/27b-3p cluster: a pilot study
Fatimah Aljubran, Amanda Graham, Wei Cui, Warren B. Nothnick
Vol 1 | No. 1 | August 2020 | Pages 90–97

Pretreatment with a gonadotropin-releasing hormone agonist and an aromatase inhibitor may improve outcomes in in vitro fertilization cycles of women with stage I–II endometriosis
Sabrina Piedimonte, Alexander Volodarsky-Perel, Samer Tannus, Seang Lin Tan, Michael H. Dahan
Vol 1 | No. 1 | August 2020 | Pages 98–103

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