December 2021

Volume 116, Issue 6

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From the Media Editor

A message From the Media Editors of the Fertility and Sterility family of journals
Micah J. Hill, M. Blake Evans, Daylon James, Pietro Bortoletto
Vol 116 | No. 6 | December 2021 | Page 1429

Views and Reviews

Recurrent implantation failure: Sapere aude
Micah J. Hill
Vol 116 | No. 6 | December 2021 | Pages 1430-1431

Defining recurrent implantation failure: a profusion of confusion or simply an illusion?
Audrey S. Garneau, Steven L. Young
Vol 116 | No. 6 | December 2021 | Pages 1432-1435

A review of the pathophysiology of recurrent implantation failure
Jason M. Franasiak, Diana Alecsandru, Eric J. Forman, Laura C. Gemmell, Jeffrey M. Goldberg, Natalia Llarena, Cheri Margolis, Joop Laven, Sam Schoenmakers, Emre Seli
Vol 116 | No. 6 | December 2021 | Pages 1436-1448

Novel therapeutic options for treatment of recurrent implantation failure
Jenna Turocy, Zev Williams
Vol 116 | No. 6 | December 2021 | Pages 1449-1454

Fertile Battle

Does my father have higher sperm counts than me?
Michael L. Eisenberg
Vol 116 | No. 6 | December 2021 | Pages 1455-1456

Are worldwide sperm counts declining?
Niels Jørgensen, Dolores J. Lamb, Hagai Levine, Alexander W. Pastuszak, John T. Sigalos, Shanna H. Swan, Michael L. Eisenberg
Vol 116 | No. 6 | December 2021 | Pages 1457-1463

Inklings

Truth telling in reproductive medicine
Robert J. Norman
Vol 116 | No. 6 | December 2021 | Pages 1464-1465

Perspectives

“Work–life balance” in medicine: has it resulted in better patient care?
Robert William Rebar
Vol 116 | No. 6 | December 2021 | Pages 1466-1467

Seminal Contributions

Do frozen embryo transfers modify the epigenetic control of imprinted genes and transposable elements in newborns compared with fresh embryo transfers and natural conceptions?
Julie Barberet, Gaelle Romain, Christine Binquet, Magali Guilleman, Céline Bruno, Perrine Ginod, Caroline Chapusot, Cécile Choux, Patricia Fauque
Vol 116 | No. 6 | December 2021 | Pages 1468-1480

Reflections: Fresh embryo transfer results in altered placental epigenetic regulation: a rationale for frozen embryo transfer
Andres Reig, Jason M. Franasiak
Vol 116 | No. 6 | December 2021 | Pages 1481-1482 

Original Articles

Andrology

Sperm DNA fragmentation index and cumulative live birth rate in a cohort of 2,713 couples undergoing assisted reproduction treatment
Sladjana Malić Vončina, Amelie Stenqvist, Mona Bungum, Tommy Schyman, Aleksander Giwercman
Vol 116 | No. 6 | December 2021 | Pages 1483-1490

Reflections: Sperm DNA fragmentation: What have we learned so far?
Philip Xie, Stephanie Cheung, Olena M. Kocur, Zev Rosenwaks, Gianpiero D. Palermo
Vol 116 | No. 6 | December 2021 | Page 1491

Assisted Reproduction

The impact of medical therapies and factors related to treatment procedures in women with rheumatoid arthritis and inflammatory bowel disease receiving assisted reproduction: a nationwide cohort study
Bente Mertz Nørgård, Mette Wod, Michael Due Larsen, Sonia Friedman, Line Riis Jølving, Jens Fedder
Vol 116 | No. 6 | December 2021 | Pages 1492-1500

Reflections: Missing an important finding: why overly generalizable studies are a double-edged sword
George Patounakis, Micah J. Hill
Vol 116 | No. 6 | December 2021 | Page 1501

Endometrial thickness changes after progesterone administration do not affect the pregnancy outcomes of frozen-thawed euploid blastocyst transfer: a retrospective cohort study
Ziqi Jin, Hao Shi, Manman Lu, Zhiqin Bu, Mingzhu Huo, Yile Zhang
Vol 116 | No. 6 | December 2021 | Pages 1502-1512

Reflections: Thickness or pattern: that is the question
Robert F. Casper, Jigal Haas, Eran Zilberberg
Vol 116 | No. 6 | December 2021 | Pages 1513-1514

Singleton pregnancies conceived with infertility treatments and the risk of neonatal and infant mortality
Gordon J. Farley, Mark V. Sauer, Justin S. Brandt, Cande V. Ananth
Vol 116 | No. 6 | December 2021 | Pages 1515-1523

Reflections: The health of in vitro fertilization-conceived children: The Blind Men and the Elephant
Barbara Luke Sc.D.
Vol 116 | No. 6 | December 2021 | Pages 1524-1525 

Relationship between semen regurgitation and pregnancy rates with intrauterine insemination
LaTasha B. Craig, Sushila Arya, Heather R. Burks, Kaitlin Warta, Christen Jarshaw, Karl R. Hansen, Jennifer D. Peck
Vol 116 | No. 6 | December 2021 | Pages 1526-1531

Media regurgitation after intrauterine insemination: Is the uterus half empty or half full?
Phillip A. Romanski, Pietro Bortoletto, Alexis P. Melnick
Vol 116 | No. 6 | December 2021 | Pages 1532-1533

Serum luteal phase progesterone in women undergoing frozen embryo transfer in assisted conception: a systematic review and meta-analysis
Pedro Melo, Yealin Chung, Oonagh Pickering, Malcolm J. Price, Simon Fishel, Mohammed Khairy, Charles Kingsland, Philip Lowe, Georgios Petsas, Madhurima Rajkhowa, Victoria Sephton, Amanda Tozer, Simon Wood, Elena Labarta, Mark Wilcox, Adam Devall, Ioannis Gallos, Arri Coomarasamy
Vol 116 | No. 6 | December 2021 | Pages 1534-1556

Reflections: Can measuring the luteal phase progesterone level bridge the divide between the Atlantic?
Samuel Santos-Ribeiro, Catarina Godinho, Sérgio Reis Soares
Vol 116 | No. 6 | December 2021 | Pages 1557-1558

Early Pregnancy

Hysteroscopic treatment and reproductive outcomes in cesarean scar pregnancy: experience at a single institution
Qin Tang, Yan Qin, Qin Zhou, Junying Tang, Qin Zhou, Jian Qiao, Chunmei Shu, Xuelin Dai, Jing Zhang
Vol 116 | No. 6 | December 2021 | Pages 1559-1566

Reflections: Is hysteroscopic treatment of cesarean scar pregnancy the best option?
Charles E. Miller, Mary M. McKenna
Vol 116 | No. 6 | December 2021 | Page 1567

Endometriosis

Prolonged cyclical and continuous regimens of dydrogesterone are effective for reducing chronic pelvic pain in women with endometriosis: results of the ORCHIDEA study
Gennady T. Sukhikh, Leila V. Adamyan, Svetlana O. Dubrovina, Igor I. Baranov, Vitaly F. Bezhenar, Andrey V. Kozachenko, Viktor E. Radzinsky, Mekan R. Orazov, Maria I. Yarmolinskaya, Jan I. Olofsson
Vol 116 | No. 6 | December 2021 | Pages 1568-1577

Reflections: Round-the-clock or start-and-stop: Does the regimen matter when dydrogesterone is used to treat chronic pelvic pain due to endometriosis?
Jennifer L. Eaton
Vol 116 | No. 6 | December 2021 | Pages 1578-1579

Early identification of women with endometriosis by means of a simple patient-completed questionnaire screening tool: a diagnostic study
Arnaud Fauconnier, Hocine Drioueche, Cyrille Huchon, Joseph Du Cheyron, Emilie Indersie, Yasmine Candau, Pierre Panel, Xavier Fritel
Vol 116 | No. 6 | December 2021 | Pages 1580-1589 

Environment

Urinary concentrations of phenols, parabens, and triclocarban in relation to uterine leiomyomata incidence and growth
Amelia K. Wesselink, Jennifer Weuve, Victoria Fruh, Traci N. Bethea, Birgit Claus Henn, Quaker E. Harmon,  Russ Hauser, Paige L. Williams, Antonia M. Calafat, Michael McClean, Donna D. Baird, Lauren A. Wise
Vol 116 | No. 6 | December 2021 | Pages 1590-1600

Fertility Preservation

Disposition intentions of elective egg freezers toward their surplus frozen oocytes: a systematic review and meta-analysis
Lucy E. Caughey, Sarah Lensen, Katherine M. White, Michelle Peate
Vol 116 | No. 6 | December 2021 | Pages 1601-1619

Reflections: The state of the science on women’s disposition decisions about electively frozen surplus eggs
Patricia E. Hershberger
Vol 116 | No. 6 | December 2021 | Pages 1620-1621

Reproductive Endocrinology

Reproductive endocrinologists’ knowledge and attitudes in the identification of intimate partner violence
Seth J. Barishansky, Periel Shapiro, Gabrielle Meyman, Mary Ellen Pavone, Angela K. Lawson
Vol 116 | No. 6 | December 2021 | Pages 1622-1630

Ovulatory upregulation of angiotensin-converting enzyme 2, a receptor for SARS-CoV-2, in dominant follicles of the human ovary
Yohan Choi, Hayce Jeon, Mats Brännström, James W. Akin, Thomas E. Curry Jr., Misung Jo
Vol 116 | No. 6 | December 2021 | Pages 1631-1640

Oxidative stress promotes hyperandrogenism by reducing sex hormone-binding globulin in polycystic ovary syndrome
Yuan Sun, Suiyan Li, Hongwei Liu, Huai Bai, Kaifeng Hu, Renjiao Zhang, Qingqing Liu, Ping Fan
Vol 116 | No. 6 | December 2021 | Pages 1641-1650

Reproductive Science

Metabolic imaging of human cumulus cells reveals associations among metabolic profiles of cumulus cells, patient clinical factors, and oocyte maturity
Marta Venturas, Xingbo Yang, Kishlay Kumar, Dagan Wells, Catherine Racowsky, Daniel J. Needleman
Vol 116 | No. 6 | December 2021 | Pages 1651-1662

Reflections: The key role of cumulus cells in oocytes in vitro maturation protocols
Noelia Nikoloff
Vol 116 | No. 6 | December 2021 | Page 1663

Videos

Using pneumovaginoscopy to perform the removal of a vaginal fibroid
Maud Allary, Aubert Agostini, Lisa Calderon, Laura Miquel, Patrice Crochet, Antoine Netter
Vol 116 | No. 6 | December 2021 | Pages 1664-1666

Reflections: Taking notes on vNOTES
Anupama Rambhatla, Luis R. Hoyos
Vol 116 | No. 6 | December 2021 | Pages 1667-1668

Falloposcopic tuboplasty: an easy, quick, and safe technique
Hidehiko Matsubayashi, Yukiko Takaya, Takumi Takeuchi, Masakazu Doshida, Yasuhiro Ohara, Tomomoto Ishikawa
Vol 116 | No. 6 | December 2021 | Pages 1669-1672

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.