Views and Reviews

Telemedicine in reproductive medicine—implications for technology and clinical practice
Mark Sigman
Vol 114 | No. 6 | December 2020 | Page 1125

Telemedicine technology and implications for reproductive office operations
Matt Uustal, Lisa Blackmon
Vol 114 | No. 6 | December 2020 | Pages 1126-1128

Clinical implications of telemedicine for providers and patients
William T. Berg, Marc Goldstein, Alexis P. Melnick, Zev Rosenwaks
Vol 114 | No. 6 | December 2020 | Pages 1129-1134

Where will telemedicine go from here?
Katherine Rotker, Danielle Velez
Vol 114 | No. 6 | December 2020 | Pages 1135-1139

Fertile Battle

What should the first-line treatment for couples with unexplained infertility be: intrauterine insemination or in vitro fertilization?
Cynthia Farquhar
Vol 114 | No. 6 | December 2020 | Page 1140

Should couples with unexplained infertility have three to six cycles of intrauterine insemination with ovarian stimulation or in vitro fertilization as first-line treatment?Willem Ombelet, Rik van Eekelen, Aine McNally, William Ledger, Kevin Doody, Cynthia Farquhar
Vol 114 | No. 6 | December 2020 | Pages 1141-1148

Inklings

The evolving role of reproductive endocrinologists in residency training in obstetrics and gynecology: addressing the balance between clinical focus and educational requirements
William D. Schlaff
Vol 114 | No. 6 | December 2020 | Pages 1149-1150

ASRM Pages

Testing and interpreting measures of ovarian reserve: a committee opinionPractice Committee of the American Society for Reproductive Medicine
Vol 114 | No. 6 | December 2020 | Pages 1151-1157

Recommendations for reducing the risk of viral transmission during fertility treatment with the use of autologous gametes: a committee opinion
Practice Committee of the American Society for Reproductive Medicine
Vol 114 | No. 6 | December 2020 | Pages 1158-1164

Reflections

Ectopic pregnancy: Why do embryos get lost along the way?
Robert T. Rydze, Kate Schoyer, Shunping Wang
Vol 114 | No. 6 | December 2020 | Page 1165

Mountains out of molehills—Are we putting too much weight on morphokinetics?
Anne P. Hutchinson
Vol 114 | No. 6 | December 2020 | Page 1166

Intergenerational programming and in vitro fertilization: another turn of the screw
Luis R. Hoyos, Daniel A. Dumesic
Vol 114 | No. 6 | December 2020 | Pages 1167-1168

Too much of a good thing? Total gonadotropin dose and in vitro fertilization outcomes
Catherine Gordon, Elizabeth Ginsburg
Vol 114 | No. 6 | December 2020 | Pages 1169-1170

Choosing the best embryo with the help of artificial intelligence
Elnur Babayev
Vol 114 | No. 6 | December 2020 | Page 1171

Preconception exposures and postconception outcomes: selection bias in action
Kerry S.J. Flannagan, Sunni L. Mumford
Vol 114 | No. 6 | December 2020 | Pages 1172-1173

Klotho: spinning up some new hype for decreased ovarian reserve research?
Trenton L. Place, Lynda K. McGinnis
Vol 114 | No. 6 | December 2020 | Page 1174

Preconception dilemma for women with obesity: Is it worth waiting to lose weight?
Helen H. Kim
Vol 114 | No. 6 | December 2020 | Pages 1175-1176

Does low-dose aspirin use impact the menstrual cycle? A hypothetical risk gets debunked
Jennifer L. Eaton
Vol 114 | No. 6 | December 2020 | Pages 1177-1178

Is there a link between focal adenomyosis and infertility?
Juan A. Garcia-Velasco
Vol 114 | No. 6 | December 2020 | Page 1179

Rubik’s cube of depression, antidepressants, and fertility
Amy Kaing, Eleni G. Jaswa
Vol 114 | No. 6 | December 2020 | Pages 1180-1181

Treating the couple: how recurrent pregnancy loss impacts the mental health of both partners
Rachel S. Ruderman, Bahar D. Yilmaz, Dana B. McQueen
Vol 114 | No. 6 | December 2020 | Pages 1182

Midgestation origins of androgenic and estrogenic pathophysiology in three major women’s health disorders
David H. Abbott, Daniel A. Dumesic
Vol 114 | No. 6 | December 2020 | Pages 1183-1184

Thyroid autoantibodies: to treat or not to treat?
Sarah Gavrizi, Robert A. Wild
Vol 114 | No. 6 | December 2020 | Pages 1185-1186

Routine assessment of ovulation is unlikely to be medically necessary among eumenorrheic women
Elizabeth A. DeVilbiss, Lindsey A. Sjaarda, Sunni L. Mumford
Vol 114 | No. 6 | December 2020 | Pages 1187-1188

Peering through frosted glass: transparency in reproductive research
Wright Bates Jr.
Vol 114 | No. 6 | December 2020 | Pages 1189-1190

New insights for fertility preservation by ovarian tissue cryopreservation and transplantation in pediatric cancer patients
Sonia Herraiz, Irene Cervelló
Vol 114 | No. 6 | December 2020 | Page 1191

Commentary on regulation of leiomyoma stem cell proliferation by WNT4 via AKT-dependent β-Catenin activation
Hortensia Ferrero
Vol 114 | No. 6 | December 2020 | Pages 1192-1193

You won't find what you're not looking for
Preston Parry
Vol 114 | No. 6 | December 2020 | Page 1194

New approaches in bloom: four-petal adenomyomectomy technique
Matthew B. Givens, Steven R. Lindheim, Linnea R. Goodman
Vol 114 | No. 6 | December 2020 | Pages 1195-1196

Laparoscopic ovarian surgery to induce follicular response in patients with premature ovarian insufficiency, diminished ovarian reserve, or resistant ovary syndrome
Nigel Pereira
Vol 114 | No. 6 | December 2020 | Page 1197

Original Articles

Assisted Reproduction

Ovarian stimulation increases the risk of ectopic pregnancy for fresh embryo transfers: an analysis of 68,851 clinical pregnancies from the Japanese Assisted Reproductive Technology registry
Seung Chik Jwa, Sachie Seto, Masashi Takamura, Akira Kuwahara, Takeshi Kajihara, Osamu Ishihara
Vol 114 | No. 6 | December 2020 | Pages 1198-1206

Randomized study of G-TL and global media for blastocyst culture in the EmbryoScope: morphokinetics, pregnancy, and live births after single-embryo transfer
Nina Desai, Meng Yao, Elliott G. Richards, Jeffrey M. Goldberg
Vol 114 | No. 6 | December 2020 | Pages 1207-1215

Is conception by in vitro fertilization associated with altered antenatal and postnatal growth trajectories?
Steve Turner, Eilidh Maclean, Smita Dick, Lorna Aucott, Abha Maheshwari
Vol 114 | No. 6 | December 2020 | Pages 1216-1224

Differential impact of controlled ovarian hyperstimulation on live birth rate in fresh versus frozen embryo transfer cycles: a Society for Assisted Reproductive Technology Clinic Outcome System study
Rachel S. Gerber, Melissa Fazzari, Michelle Kappy, Alexa Cohen, Sharon Galperin, Harry Lieman, Sangita Jindal, Erkan Buyuk
Vol 114 | No. 6 | December 2020 | Pages 1225-1231

Novel and conventional embryo parameters as input data for artificial neural networks: an artificial intelligence model applied for prediction of the implantation potential
Lorena Bori, Elena Paya, Lucia Alegre, Thamara Alexandra Viloria, Jose Alejandro Remohi, Valery Naranjo, Marcos Meseguer
Vol 114 | No. 6 | December 2020 | Pages 1232-1241

Epidemiology

Reproductive sequelae of parental severe illness before the pandemic: implications for the COVID-19 pandemic
Alex M. Kasman, Hriday P. Bhambhvani, Shufeng Li, Chiyuan A. Zhang, David K. Stevenson, Gary M. Shaw, Julia F. Simard, Michael L. Eisenberg
Vol 114 | No. 6 | December 2020 | Pages 1242-1249

Genetics

Low KLOTHO level related to aging is associated with diminished ovarian reserve
Xiaofei Xu, Yongxiu Hao, Qihang Zhong, Jing Hang, Yue Zhao, Jie Qiao
Vol 114 | No. 6 | December 2020 | Pages 1250-1255

Gynecology 

Time to pregnancy after a prepregnancy very-low-energy diet program in women with obesity: substudy of a randomized controlled trial
Sarah A. Price, Priya Sumithran, Luke A. Prendergast, Alison J. Nankervis, Michael Permezel, Joseph Proietto
Vol 114 | No. 6 | December 2020 | Pages 1256-1262

Low-dose aspirin in reproductive health: effects on menstrual cycle characteristics
Blake Evans, Carrie J. Nobles, Keewan Kim, Micah J. Hill, Alan H. DeCherney, Robert M. Silver, Sunni L. Mumford, Lindsey A. Sjaarda, Neil J. Perkins, Enrique F. Schisterman
Vol 114 | No. 6 | December 2020 | Pages 1263-1270

Infertility

Focal adenomyosis is associated with primary infertility
Mathilde Bourdon, Pietro Santulli, Joana Oliveira, Louis Marcellin, Chloé Maignien, Léa Melka, Corinne Bordonne, Anne-Elodie Millisher, Geneviève Plu-Bureau, Julie Cormier, Charles Chapron
Vol 114 | No. 6 | December 2020 | Pages 1271-1277

Mental Health

Urinary selective serotonin reuptake inhibitors across critical windows of pregnancy establishment: a prospective cohort study of fecundability and pregnancy loss
Lindsey A. Sjaarda, Jeannie G. Radoc, Kerry S. Flannagan, Sunni L. Mumford, Keewan Kim, Neil J. Perkins, Robert M. Silver, Enrique F. Schisterman
Vol 114 | No. 6 | December 2020 | Pages 1278-1287

Recurrent pregnancy loss: a shared stressor---couple-orientated psychological research findings
Pauline Voss, Maren Schick, Laila Langer, Asrin Ainsworth, Beate Ditzen, Thomas Strowitzki, Tewes Wischmann, Ruben J. Kuon
Vol 114 | No. 6 | December 2020 | Pages 1288-1296

Reproductive Endocrinology

Anthropometric biomarkers for abnormal prenatal reproductive hormone exposure in women with Mayer-Rokitanksy-Küster-Hauser syndrome, polycystic ovary syndrome, and endometriosis
Henrike E. Peters, Claire H.C. Laeven, Constantia J.M.A. Trimbos, Peter M. van de Ven,
Marieke O. Verhoeven, Roel Schats, Velja Mijatovic, Cornelis B. Lambalk
Vol 114 | No. 6 | December 2020 | Pages 1297-1305

Effect of levothyroxine on pregnancy outcomes in women with thyroid autoimmunity: a systematic review with meta-analysis of randomized controlled trials
Xing Wang, Yu Zhang, Huiwen Tan, Yu Bai, Liangxue Zhou, Fang Fang, Andrew Faramand, Weelic Chong, Yang Hai
Vol 114 | No. 6 | December 2020 | Pages 1306-1314

Revisiting the role of serum progesterone as a test of ovulation in eumenorrheic subfertile women: a prospective diagnostic accuracy study
Parimala Chinta, Grace Rebekah, Aleyamma T Kunjummen, Mohan S. Kamath
Vol 114 | No. 6 | December 2020 | Pages 1315-1321

Reproducible research practices and transparency in reproductive endocrinology and infertility articles
James M. Kemper, Daniel L. Rolnik, Ben W.J. Mol, John P.A. Ioannidis
Vol 114 | No. 6 | December 2020 | Pages 1322-1329

Reproductive Science

Follicle populations and vascularization in ovarian tissue of pediatric patients before and after long-term grafting
Rossella Masciangelo, Maria Costanza Chiti, Charlotte Philippart, Christiani Andrade Amorim, Jacques Donnez, Alessandra Camboni, Marie-Madeleine Dolmans
Vol 114 | No. 6 | December 2020 | Pages 1330-1338

Activation of protein kinase B by WNT4 as a regulator of uterine leiomyoma stem cell function
Shimeng Liu, Ping Yin, Ariel J. Dotts, Stacy A. Kujawa, John S. Coon V, Jian-Jun Wei, Debabrata Chakravarti, Serdar E. Bulun
Vol 114 | No. 6 | December 2020 | Pages 1339-1349

Video

Hidden spaces: treatment of an occult uterovaginal septum
John A. Occhino, Chandra C. Shenoy, Zaraq Khan
Vol 114 | No. 6 | December 2020 | Pages 1350-1351

Performing laparoscopic adenomyomectomy with the four-petal method
Hsin-Hong Kuo, Cindy Hsuan Weng, Amruta Jaiswal, Kai-Yun Wu, Chin-Jung Wang, Chyi-Long Lee, Chih-Feng Yen
Vol 114 | No. 6 | December 2020 | Pages 1352-1354

Surgical approaches of drug-free in vitro activation and laparoscopic ovarian incision to treat patients with ovarian infertility
Yuka Tanaka, Aaron J. Hsueh, Kazuhiro Kawamura
Vol 114 | No. 6 | December 2020 | Pages 1355-1357