Darwin meets Mendel in the reproductive medicine field: Homo sapiens 2.0 is inevitable

Darwin meets Mendel in the reproductive medicine field: Homo sapiens 2.0 is inevitable

VOLUME 115, ISSUE 4, P850-851


Jeanne E. O’Brien, M.D., M.S., Eli Y. Adashi, M.D., M.S., Carlos Simon, M.D., Ph.D. 


Reproductive Endocrinology and Infertility (REI) was officially recognized as a subspecialty in the United States in 1972. The first US baby born as a result of in vitro fertilization dates back to 1981. Since then, the field of reproductive medicine has witnessed dramatic medical and technological advances. Our relatively new subspecialty accounts for more than 8 million births, a drop in the ocean of the 7,625 million worldwide, but our field has just started.

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Go to the profile of Pandiyan  Natarajan
over 1 year ago
Darwin meets Mendel in the reproductive medicine field: Homo sapiens2.0 is inevitable- An Utopian idea.

I enjoyed reading the views expressed in the article. However these views appear Utopian. There have been too many False starts and False hopes raised in medicine, and I think this is one of them. Homo sapiens 2.0 or Meta Human or Homo Deus are catchy titles, but no where near reality.

When the structure of DNA was hypothesized, it was claimed that, ‘The secret of Life,’ has been revealed. Now after 68 years we still don’t know the definition of life. We have not been able to create a new life, despite having known, ‘The secret of Life.’

When the Human Genome was unveiled we made another claim that we have got the blue print and have identified all the letters which go to form the Human body. Yet, 21 years later, there are very few conditions which we have been able to treat by Genetic Therapy.

CRISPR- Cas 9 is expected to revolutionize biological sciences including Medicine. However,  this claim is yet to be substantiated in medical practice. This precision editing ( like precision bombing ) of the Human Genome is not, after all so precise. What indels are likely to happen is not yet known. 

I am NOT being Pessimistic; but having seen the tall claims that have been made over the last 44 years I am in the field, I would like to exercise considerable caution.

Many human traits are not single gene traits. Single genes perform several functions and several genes together perform single function. To DESIGN a. BABY with desired characteristics at this point in time and in the foreseeable future looks UTOPIAN.

Professor Dr Pandiyan Natarajan,

Professor and Head of the Department of Andrology and Reproductive Medicine.

Chettinad Super Speciality Hospital,

Chettinad Academy of Research and Education,

 Kelambakkam, Tamil Nadu,