Comparison of fertility outcomes after laparoscopic myomectomy for barbed versus nonbarbed sutures

The use of barbed sutures during laparoscopic myomectomy appears to lead to the same obstetric outcomes as traditional smooth filaments.

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VOLUME 115, ISSUE 1, P248-255


Alessandro Arena, M.D., Eugenia Degli Esposti, M.D., Giulia Cristani, M.D., Benedetta Orsini, M.D., Elisa Moro, M.D., Diego Raimondo, M.D., Simona Del Forno, M.D., Ph.D., Jacopo Lenzi, Paolo Casadio, M.D., Renato Seracchioli, M.D.



To assess the impact on women’s reproductive outcomes of barbed sutures to repair uterine breaches during laparoscopic myomectomy compared with traditional smooth sutures.


Retrospective, monocentric cohort study, with information on subsequent pregnancies prospectively acquired for some women.


Tertiary-level academic referral center.


Women older than 18 years who had undergone a laparoscopic myomectomy and had sought pregnancy afterward, divided into two groups based on type of suture used to repair the uterine wall: group A (nonbarbed) and group B (barbed).


Laparoscopic removal of FIGO types 3, 4, 5, and 6 uterine leiomyomas by use of either only barbed sutures or only traditional smooth sutures to reconstruct the uterine defect.

Main Outcome Measure(s)

Pregnancy achievement rates, delivery modes, main pregnancy complications, perioperative complications for both kinds of suture, and the trend of the use of barbed sutures over time at our center.


Of 164 patients included, 83 were in group A and 81 in group B. Ninety-one patients (55.5%) experienced at least one postoperative pregnancy, with no differences between the groups (group A 60.5%; group B 50.6%). Of the 103 recorded postoperative pregnancies, 70 (68%) resulted in live births, 29 (28.1%) in first-trimester miscarriages, and 4 (3.9%) were ongoing.


Barbed sutures have a similar impact on reproductive outcomes as smooth conventional threads, both in terms of pregnancy and obstetric complication rates, after laparoscopic myomectomy.

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.