Volume 1, Issue 1, Pages 48–50
Authors:
Qizhen Zheng, M.D., Shiru Xu, M.D., Meilan Mo, M.D., Jing You, B.D., Yong Zeng, M.D.
Abstract:
Objective
To report a very rare case of live birth with unexpectedly low serum hCG level on day 11 after blastocyst embryo transfer.
Design
Case report.
Setting
Private infertility center.
Patient(s)
A 30-year-old nulliparous woman presented with PCOS and 1 year of infertility.
Interventions(s)
Conventional IVF was scheduled and a long-acting agonist protocol was selected.
Main Outcome Measure(s)
Maternal serum hCG levels and transvaginal ultrasound exams for the embryo’s well-being.
Result(s)
The hCG level was 11.6 IU/L on day 11 after the transfer of two blastocyst embryos, which was considered as either failing or extrauterine pregnancy. After blood titration, there were delayed hCG increases. A series of transvaginal ultrasounds also indicated a delayed but normal-appearing intrauterine pregnancy. A healthy baby boy was delivered at term by means of cesarean section.
Conclusion(s)
A low initial serum hCG level may be associated with certain maternal or fetal characteristics and IVF treatment variables. Close conservative observation is warranted before undertaking any therapeutic intervention.
