Peritoneal fluid in the pouch of Douglas Strategically located and affecting reproductive events

The classic paradigm describing the physiology of reproduction in women relies mainly on the hypothalamic-pituitary-ovarian axis. The ovarian steroids estradiol and progesterone control endometrial development in a cyclic pattern to achieve implantation and maintain pregnancy. This process is regulated predominantly by the endocrine and paracrine systems acting through neurons, blood vessels, and nearby cell-to-cell mechanisms. The potential contribution of free peritoneal fluid (PF) in the pouch of Douglas to the regulation of female reproductive processes has not yet been comprehensively investigated or understood in normal or pathologic conditions.

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Authors

Johnny S. Younis, M.D., Neri Laufer, M.D.

Volume 104, Issue 4, Pages 831-832

Abstract

The classic paradigm describing the physiology of reproduction in women relies mainly on the hypothalamic-pituitary-ovarian axis. The ovarian steroids estradiol and progesterone control endometrial development in a cyclic pattern to achieve implantation and maintain pregnancy. This process is regulated predominantly by the endocrine and paracrine systems acting through neurons, blood vessels, and nearby cell-to-cell mechanisms. The potential contribution of free peritoneal fluid (PF) in the pouch of Douglas to the regulation of female reproductive processes has not yet been comprehensively investigated or understood in normal or pathologic conditions.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)01847-6/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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