External validation of the Endometriosis Fertility Index in a French population

The Endometriosis Fertility Index (EFI) predicted spontaneous pregnancy after surgery for endometriotic infertile women. Combining surgery and assisted reproductive technologies according to EFI led to a 78% pregnancy rate at 18 months.

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Authors

Jeremy Boujenah, M.D., Claire Bonneau, M.D., Jean-Noel Hugues, M.D., Ph.D., Christophe Sifer, M.D., Christophe Poncelet, M.D., Ph.D.

Volume 104, Issue 1, Pages 119–123

Abstract

Objective:

To show an external validation of the Endometriosis Fertility Index (EFI) and to observe cumulated pregnancy rates after infertility management combining surgery and assisted reproductive technologies (ART).

Design:

Observational study from January 2004 to December 2012.

Setting:

Tertiary-care university hospital and ART center.

Patient(s):

Four hundred twelve infertile and endometriotic patients after laparoscopic surgery.

Intervention(s):

Surgical diagnosis and treatment followed by spontaneous fertility or ART management.

Main Outcome Measure(s):

Spontaneous pregnancy rates and cumulative (spontaneous and ART) pregnancy rates according to the EFI.

Result(s):

A significant relationship between EFI and spontaneous pregnancy rates was observed at 12 months (P=.001). The least function score and complete removal of endometriotic lesions and pelvic adhesions were significantly associated with spontaneous pregnancy (P=.006). Cumulative pregnancy rate at 18 months was 78.8%. ART benefits for pregnancy rates were higher for patients with poor EFI.

Conclusion(s):

External validation of the EFI in a French population was demonstrated. Combining surgery for endometriosis and ART led to a 78.8% pregnancy rate at 18 months after surgery.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00233-2/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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