External validation of the Endometriosis Fertility Index in a French population
The Endometriosis Fertility Index (EFI) predicted spontaneous pregnancy after surgery for endometriotic infertile women. Combining surgery and assisted reproductive technologies according to EFI led to a 78% pregnancy rate at 18 months.
Authors
Jeremy Boujenah, M.D., Claire Bonneau, M.D., Jean-Noel Hugues, M.D., Ph.D., Christophe Sifer, M.D., Christophe Poncelet, M.D., Ph.D.
Volume 104, Issue 1, Pages 119–123
Abstract
Objective:
To show an external validation of the Endometriosis Fertility Index (EFI) and to observe cumulated pregnancy rates after infertility management combining surgery and assisted reproductive technologies (ART).
Design:
Observational study from January 2004 to December 2012.
Setting:
Tertiary-care university hospital and ART center.
Patient(s):
Four hundred twelve infertile and endometriotic patients after laparoscopic surgery.
Intervention(s):
Surgical diagnosis and treatment followed by spontaneous fertility or ART management.
Main Outcome Measure(s):
Spontaneous pregnancy rates and cumulative (spontaneous and ART) pregnancy rates according to the EFI.
Result(s):
A significant relationship between EFI and spontaneous pregnancy rates was observed at 12 months (P=.001). The least function score and complete removal of endometriotic lesions and pelvic adhesions were significantly associated with spontaneous pregnancy (P=.006). Cumulative pregnancy rate at 18 months was 78.8%. ART benefits for pregnancy rates were higher for patients with poor EFI.
Conclusion(s):
External validation of the EFI in a French population was demonstrated. Combining surgery for endometriosis and ART led to a 78.8% pregnancy rate at 18 months after surgery.
Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00233-2/fulltext
No comments yet.