External validation of the Endometriosis Fertility Index in a French population

The Endometriosis Fertility Index (EFI) predicted spontaneous pregnancy after surgery for endometriotic infertile women. Combining surgery and assisted reproductive technologies according to EFI led to a 78% pregnancy rate at 18 months.

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Authors

Jeremy Boujenah, M.D., Claire Bonneau, M.D., Jean-Noel Hugues, M.D., Ph.D., Christophe Sifer, M.D., Christophe Poncelet, M.D., Ph.D.

Volume 104, Issue 1, Pages 119–123

Abstract

Objective:

To show an external validation of the Endometriosis Fertility Index (EFI) and to observe cumulated pregnancy rates after infertility management combining surgery and assisted reproductive technologies (ART).

Design:

Observational study from January 2004 to December 2012.

Setting:

Tertiary-care university hospital and ART center.

Patient(s):

Four hundred twelve infertile and endometriotic patients after laparoscopic surgery.

Intervention(s):

Surgical diagnosis and treatment followed by spontaneous fertility or ART management.

Main Outcome Measure(s):

Spontaneous pregnancy rates and cumulative (spontaneous and ART) pregnancy rates according to the EFI.

Result(s):

A significant relationship between EFI and spontaneous pregnancy rates was observed at 12 months (P=.001). The least function score and complete removal of endometriotic lesions and pelvic adhesions were significantly associated with spontaneous pregnancy (P=.006). Cumulative pregnancy rate at 18 months was 78.8%. ART benefits for pregnancy rates were higher for patients with poor EFI.

Conclusion(s):

External validation of the EFI in a French population was demonstrated. Combining surgery for endometriosis and ART led to a 78.8% pregnancy rate at 18 months after surgery.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00233-2/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.