Expression of miR-29c is suppressed and inversely correlated with collagen and DNMT3A in leiomyoma. The suppression of miR-29c in leiomyoma smooth muscle cells is primarily mediated by specific protein 1, NF-kB signaling, and epigenetic modification.

MicroRNAs can be reproducibly detected in blastocyst-spent media and most likely belong to trophectoderm cells. Primary clinical data suggest testing these noninvasive biomarkers for embryo selection in IVF cycles.

The gonadotropin-releasing hormone analogues inhibit fibrosis even in the presence of gonadal hormones in immortalized human leiomyoma cells grown in three-dimensional cultures.

Serum AMH levels are relatively high in the late follicular phase of the menstrual cycle, but the increase is small and not seen in young (< 31 years) women