Mike Ripley, M.D., F.R.C.S.C., Andrea Lanes, M.Sc., Marie-Claude Léveillé, Ph.D., Doron Shmorgun, M.D., F.R.C.S.C.
Volume 103, Issue 5, Pages 1170-1175
To compare reproductive outcomes of patients with very low, low, normal, and high antral follicle counts undergoing unstimulated therapeutic donor insemination (TDI) cycles.
Retrospective cohort study.
University-affiliated regional fertility clinic.
Four hundred fifty-nine patients who had 1,107 TDI treatment cycles from January 2006 to December 2013.
Unstimulated therapeutic donor insemination.
Main Outcome Measure(s):
Clinical pregnancy rates and miscarriage rates as surrogate markers for oocyte quality.
The overall pregnancy rate per cycle start was 12.46% in the study population. There was no difference in per-cycle or cumulative pregnancy rates among patients with very low, low, average, or high antral follicle counts within each patient age group of ≤35, 36–39, and ≥40 years. The overall miscarriage rate per pregnancy was 13.61%. When stratified by patient age, there was no correlation between miscarriage rate and antral follicle count.
AFC is not a predictor of pregnancy or miscarriage rates in patients undergoing unstimulated TDI.
Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00065-5/fulltext