Authors

Mike Ripley, M.D., F.R.C.S.C., Andrea Lanes, M.Sc., Marie-Claude Léveillé, Ph.D., Doron Shmorgun, M.D., F.R.C.S.C.

Volume 103, Issue 5, Pages 1170-1175

Abstract

Objective:

To compare reproductive outcomes of patients with very low, low, normal, and high antral follicle counts undergoing unstimulated therapeutic donor insemination (TDI) cycles.

Design:

Retrospective cohort study.

Setting:

University-affiliated regional fertility clinic.

Patient(s):

Four hundred fifty-nine patients who had 1,107 TDI treatment cycles from January 2006 to December 2013.

Intervention(s):

Unstimulated therapeutic donor insemination.

Main Outcome Measure(s):

Clinical pregnancy rates and miscarriage rates as surrogate markers for oocyte quality.

Result(s):

The overall pregnancy rate per cycle start was 12.46% in the study population. There was no difference in per-cycle or cumulative pregnancy rates among patients with very low, low, average, or high antral follicle counts within each patient age group of ≤35, 36–39, and ≥40 years. The overall miscarriage rate per pregnancy was 13.61%. When stratified by patient age, there was no correlation between miscarriage rate and antral follicle count.

Conclusion(s):

AFC is not a predictor of pregnancy or miscarriage rates in patients undergoing unstimulated TDI.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00065-5/fulltext