Authors

Jose C. Vanegas, M.D., Myriam C. Afeiche, Ph.D., Audrey J. Gaskins, Sc.D., Lidia Mínguez-Alarcón, Ph.D., Paige L. Williams, Ph.D., Diane L. Wright, D.L., Ph.D., Thomas L. Toth, M.D., Russ Hauser, M.D., Sc.D., Jorge E. Chavarro, M.D., Sc.D.

Volume 103, Issue 3, Pages 749-755

Abstract

Objective:

To study the relation of dietary phytoestrogens intake and clinical outcomes of women undergoing infertility treatment with the use of assisted reproductive technology (ART).

Design:

Prospective cohort study.

Setting:

Fertility center.

Patient(s):

A total of 315 women who collectively underwent 520 ART cycles from 2007 to 2013.

Intervention(s):

None.

Main Outcome Measure(s):

Implantation, clinical pregnancy, and live birth rates per initiated cycle.

Result(s):

Soy isoflavones intake was positively related to live birth rates in ART. Compared with women who did not consume soy isoflavones, the multivariable-adjusted odds ratios of live birth (95% confidence interval) for women in increasing categories of soy isoflavones intake were 1.32 (0.76–2.27) for women consuming 0.54–2.63 mg/d, 1.87 (1.12–3.14) for women consuming 2.64–7.55 mg/d, and 1.77 (1.03–3.03) for women consuming 7.56–27.89 mg/d.

Conclusion(s):

Dietary soy intake was positively related to the probability of having a live birth during infertility treatment with ART.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)02529-1/fulltext