Hysterosalpingo foam sonography A less painful procedure for tubal patency testing during fertility workup compared to serial hysterosalpingography A randomized controlled trial

Hysterosalpingo-foam sonography (HyFoSy) is a less painful office procedure for tubal patency testing during the fertility work-up compared to hysterosalpingography.

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Authors

Kim Dreyer, M.D., Renee Out, M.D., Peter G. Hompes, M.D., Ph.D., Velja Mijatovic, M.D., Ph.D.

Volume 102, Issue 3, Pages 821-825

Abstract

Objective:

To determine whether hysterosalpingo-foam sonography (HyFoSy) is a less painful first line tubal patency test than serial hysterosalpingography (HSG).

Design:

A two-center, prospective, open-label, randomized, controlled trial.

Setting:

University hospital and teaching hospital.

Patient(s):

40 subfertile women, ages 18 to 41 years, with an indication for tubal patency testing as part of the fertility workup according to the Dutch Nederlandse Vereniging voor Obsteterie & Gynaecologie-guidelines.

Intervention(s):

Tubal patency testing by HyFoSy versus serial HSG.

Main Outcome Measure(s):

Visual Analogue Scale (VAS) pain scores during tubal patency testing.

Result(s):

The median VAS score for pain perception during the HyFoSy procedure was 1.7 cm (interquartile range: 2.1) compared with 3.7 cm (interquartile range: 4.2) during HSG. The HyFoSy procedure also had a statistically significantly shorter procedure time compared with HSG, with a median of 5.0 minutes (interquartile range: 3.0) for HyFoSy versus 12.5 minutes (interquartile range: 16.0) for HSG.

Conclusion(s):

The HyFoSy procedure is a less painful and less time-consuming tubal patency test compared with HSG.

Clinical Trial Registration Number:

Netherlands National Trial Register NTR3457.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)00505-6/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.