On label and off label drug use in the treatment of female infertility

Female infertility is often treated with both off-label medications and those approved by the US Food and Drug Administration. This review describes commonly used drugs for this indication.

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Authors

Rebecca S. Usadi, M.D., Kathryn S. Merriam, B.A.

Volume 103, Issue 3, Pages 583-594

Abstract

Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. The purpose of this article is to review the uses of both off-label treatments and those approved by the US Food and Drug Administration for female infertility, by examining the mechanism of action, the side-effect profile, fetal anomaly risks, and contraindications for the various drugs.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00048-5/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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