On label and off label drug use in the treatment of female infertility

Female infertility is often treated with both off-label medications and those approved by the US Food and Drug Administration. This review describes commonly used drugs for this indication.


Rebecca S. Usadi, M.D., Kathryn S. Merriam, B.A.

Volume 103, Issue 3, Pages 583-594


Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. The purpose of this article is to review the uses of both off-label treatments and those approved by the US Food and Drug Administration for female infertility, by examining the mechanism of action, the side-effect profile, fetal anomaly risks, and contraindications for the various drugs.

Read the full text at: http://www.fertstert.org/article/S0015-0282(15)00048-5/fulltext