First reported case of sextuplets conceived via letrozole for ovulation induction
Monitoring of follicular growth should be considered in ovulation induction with letrozole to reduce the risk of high-order multiple gestations.
Authors
Gunwant Warraich, M.D., Tannys D.R. Vause, M.D.
Volume 103, Issue 2, Pages 535-536
Abstract
Objective:
To report the first case of sextuplets conceived via letrozole during ovulation induction.
Design:
Case report.
Setting:
Private fertility clinic.
Patient(s):
32-year-old female with a history of secondary infertility and polycystic ovary syndrome.
Intervention(s):
Letrozole, 7.5 mg, on cycle days 3–7 after a progesterone-induced menses.
Main Outcome Measure(s):
Clinical pregnancy.
Result(s):
Sexchorionic-sexamniotic pregnancy.
Conclusion(s):
High-order multiple gestations are possible with letrozole ovulation induction, so patients should be counseled appropriately and follicle monitoring considered.
Read the full text at: http://www.fertstert.org/article/S0015-0282(14)02300-0/fulltext
