First reported case of sextuplets conceived via letrozole for ovulation induction

Monitoring of follicular growth should be considered in ovulation induction with letrozole to reduce the risk of high-order multiple gestations.

Like Comment

Authors

Gunwant Warraich, M.D., Tannys D.R. Vause, M.D.

Volume 103, Issue 2, Pages 535-536

Abstract

Objective:

To report the first case of sextuplets conceived via letrozole during ovulation induction.

Design:

Case report.

Setting:

Private fertility clinic.

Patient(s):

32-year-old female with a history of secondary infertility and polycystic ovary syndrome.

Intervention(s):

Letrozole, 7.5 mg, on cycle days 3–7 after a progesterone-induced menses.

Main Outcome Measure(s):

Clinical pregnancy.

Result(s):

Sexchorionic-sexamniotic pregnancy.

Conclusion(s):

High-order multiple gestations are possible with letrozole ovulation induction, so patients should be counseled appropriately and follicle monitoring considered.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)02300-0/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.