Role of assisted hatching in in vitro fertilization A guideline

This guideline document reviews the safety and efficacy of assisted hatching.


Practice Committee of the American Society for Reproductive Medicine

Volume 102, Issue 2, Pages 348–351


There is good evidence that assisted hatching (AH) slightly improves clinical pregnancy rates, particularly in poor prognosis patients, including those with prior failed in vitro fertilization (IVF) cycles. Due to a limited number of studies, there is insufficient evidence to conclude that AH improves live-birth rates. This document replaces the 2008 American Society for Reproductive Medicine and Society for Assisted Reproductive Technology Practice Committees’ document titled, “Assisted hatching in in vitro fertilization: a review of the literature. A committee opinion” (Fertil Steril 2008;90[Suppl 5]:S196–8).

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