Perinatal outcome after fetal reduction from twin to singleton To reduce or not to reduce

Reduction of twin pregnancies to singletons is associated with improved perinatal outcome.


Jigal Haas, M.D., Aya Mohr Sasson, M.D., Eran Barzilay, M.D., Ph.D., Shali Mazaki Tovi, M.D., Raoul Orvieto, M.D., Boaz Weisz, M.D., Shlomo Lipitz, M.D., Yoav Yinon, M.D.

Volume 103, Issue 2, Pages 428-432



To determine whether reduction of twin gestation to singleton pregnancy is associated with improved perinatal outcome.


A retrospective cohort study.


Single tertiary care medical center.


A cohort of 63 singleton pregnancies after reduction from dichorionic-diamniotic twins gestation and 62 dichorionic-diamniotic nonreduced twins.


Fetal reduction between 11 and 14 weeks of gestation.

Main Outcome Measure(s):

Obstetric outcome.


The rates of preterm delivery at


Fetal reduction of twins to singleton is associated with a lower risk of prematurity and superior perinatal outcome compared with nonreduced twins. Therefore, the option of fetal reduction should be considered in certain cases of twin pregnancies, where the risk for adverse outcome seems exceptionally high.

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