Birth weight is associated with inner cell mass grade of blastocysts
Blastocysts with a more developed inner cell mass developed into newborns with a greater weight, when corrected for gestational age and gender.
Authors
Frederick Licciardi, M.D., Caroline McCaffrey, Ph.D., Cheongeun Oh, Ph.D., Cecilia Schmidt-Sarosi, M.D., David McCulloh, Ph.D.
Volume 103, Issue 2, Pages 382-387
Abstract
Objective:
To determine the relationship between blastocyst growth parameters and birth weight.
Design:
Cohort study.
Setting:
University-affiliated fertility center.
Patient(s):
In vitro patients who delivered a singleton after a single-blastocyst transfer.
Intervention(s):
None.
Main Outcome Measure(s):
Birth weight adjusted for gestational age at delivery and gender, with adjusted birth weight examined for association with blastocyst scores and grades.
Result(s):
After standard in vitro fertilization (IVF) and thawed embryo transfers, greater birth weight was associated with a higher inner cell mass grade. The grade of the trophectoderm and stage of the blastocyst did not relate to weight.
Conclusion(s)
Embryonic growth as early as day 5 can predict the progress of fetal development as measured by birth weight.
Read the full text at: http://www.fertstert.org/article/S0015-0282(14)02299-7/fulltext
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