Dietary fatty acid intakes and asthenozoospermia A case control study

The high intake of saturated and trans-fats was positively related to asthenozoospermia. Dietary omega-3 polyunsaturated fatty acids are dose dependently and inversely associated with reduced odds of asthenozoospermia.

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Authors

Ghazaleh Eslamian, M.Sc., Naser Amirjannati, M.D., Bahram Rashidkhani, M.D., Ph.D., Mohammad-Reza Sadeghi, Ph.D., Ahmad-Reza Baghestani, Ph.D., Azita Hekmatdoost, M.D., Ph.D.

Volume 103, Issue 1, Pages 190-198

Abstract

Objective:

To investigate the association between dietary fatty acids intakes and asthenozoospermia.

Design:

Case-control study.

Setting:

Infertility clinics.

Patient(s):

A total of 107 men with incident asthenozoospermia and 235 age-matched controls.

Intervention(s):

None.

Main Outcome Measure(s):

Assessments of dietary intakes, semen quality, anthropometry, endocrine parameters, and demographic information.

Result(s):

According to the fully adjusted model, being in the highest tertile of total saturated fatty acids (odds ratio [OR] = 1.85, 95% confidence interval [CI] 1.24–2.96), total trans-fatty acids (OR = 2.53, 95% CI 1.54–3.92), palmitic acid (OR = 1.90, 95% CI 1.26–2.74), and stearic acid (OR = 2.13, 95% CI 1.29–3.88) was positively associated with asthenozoospermia. Whereas higher intakes of omega-3 polyunsaturated (OR = 0.68, 95% CI 0.58–0.94) and of docosahexaenoic (OR = 0.53, 95% CI 0.29–0.89) fatty acids were significantly associated with reduced odds of asthenozoospermia.

Conclusion(s):

Our findings suggest that the high intake of saturated and trans-fats was positively related to the odds of having asthenozoospermia. Conversely, inverse and dose-dependent associations were found between asthenozoospermia and intake of omega-3 polyunsaturated fatty acids. The observed associations of different types of fatty acids underline the importance of the type of fat in the etiology of asthenozoospermia.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)02260-2/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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