We need a prospective varicocelectomy trial

Controversy exists whether varicocelectomy improves pregnancy rates in couples with male infertility.

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Authors

J. C. Trussell, M.D., Dana A. Ohl, M.D., Stephen A. Krawetz, Ph.D., Peter J. Snyder, M.D.,Alex J. Polotsky, M.D., Pasquale Patrizio, M.D., M.B.E., Gregory M. Christman, M.D.

Volume 101, Issue 6, Pages 1563–1564.e1

Abstract

Controversy exists whether varicocelectomy improves pregnancy rates in couples with male infertility. Unfortunately, the majority of data come from retrospective, poorly controlled studies (1), resulting in inadequate evidence regarding the efficacy of this procedure in improving semen quality (2, 3). In addition, results from randomized, controlled trials are conflicting and methodologically of poor quality because of heterogeneous inclusion criteria, limited enrollment, and high dropout rates.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)00194-0/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.