We need a prospective varicocelectomy trial

Controversy exists whether varicocelectomy improves pregnancy rates in couples with male infertility.

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Authors

J. C. Trussell, M.D., Dana A. Ohl, M.D., Stephen A. Krawetz, Ph.D., Peter J. Snyder, M.D.,Alex J. Polotsky, M.D., Pasquale Patrizio, M.D., M.B.E., Gregory M. Christman, M.D.

Volume 101, Issue 6, Pages 1563–1564.e1

Abstract

Controversy exists whether varicocelectomy improves pregnancy rates in couples with male infertility. Unfortunately, the majority of data come from retrospective, poorly controlled studies (1), resulting in inadequate evidence regarding the efficacy of this procedure in improving semen quality (2, 3). In addition, results from randomized, controlled trials are conflicting and methodologically of poor quality because of heterogeneous inclusion criteria, limited enrollment, and high dropout rates.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)00194-0/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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