Perinatal outcome of twin pregnancies after early transvaginal multifetal pregnancy reduction

The perinatal outcome of twin pregnancies after early transvaginal fetal reduction from triplets is equivalent to the outcome of nonreduced twin pregnancies.

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Authors

Jigal Haas, M.D., Ariel Hourvitz, M.D., Jehoshua Dor, M.D., Shai Elizur, M.D., Yoav Yinon, M.D., Eran Barzilay, M.D., Ph.D., Adrian Shulman, M.D.

Volume 101, Issue 5, Pages 1344–1348

Abstract

Objective:

To compare the pregnancy outcomes of twin pregnancies following early transvaginal multifetal pregnancy reduction (MPR) with nonreduced twin gestations.

Design:

Prospective cohort study.

Setting:

Two tertiary medical centers.

Patient(s):

A cohort of 77 multiple pregnancies after reduction to twins and 78 dichorionic-diamniotic nonreduced twins.

Intervention(s):

Early fetal reduction.

Main Outcome Measure(s):

Pregnancy outcome.

Result(s):

Triplet pregnancies reduced to twins (n = 55) and nonreduced twin pregnancies (n = 78) had comparable outcomes. The rates of preterm delivery ≤32 weeks (1.9% vs. 1.4%) and ≤34 weeks of gestation (15.1% vs. 19.2%) were similar among both groups. There was no difference in the mean gestational age (36.54 vs. 36.35 weeks) or mean birth weight (2,365 vs. 2,365 g) between the two groups. Similarly, there was no significant difference in the incidence of gestational diabetes (15.1% vs. 14.1%) and intrauterine growth retardation (IUGR; 1.9% vs. 9%) between the two groups. The incidence of gestational hypertension was higher in the study group (24.5% vs. 9%), but it was not associated with an increased risk for prematurity or IUGR.

Conclusion:

The perinatal outcome of twin pregnancies after early transvaginal fetal reduction from triplets seems to be comparable to the outcome of nonreduced twin pregnancies.

Read the full text at: http://www.fertstert.org/article/S0015-0282(14)00080-6/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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