Deep endometriosis and bladder and detrusor functions in women without urinary symptoms A pilot study through an unexplored world

Deep endometriosis may impair visceral and motor function owing to fibrotic neural involvement. Our pilot study seems to showthatdetrusor function could be significantly compromised, even in asymptomatic women.

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Authors

Maurizio Serati, M.D., Elena Cattoni, M.D., Andrea Braga, M.D., Stefano Uccella, M.D., Antonella Cromi, M.D., Fabio Ghezzi, M.D.

Volume 100, Issue 5, Pages 1332-1336, November 2013

Abstract

Objective:

To evaluate the impact of deep endometriosis (DE) on bladder function, focusing on detrusor pattern, in patients without preoperative urinary symptoms.

Design:

Prospective study.

Setting:

Academic research center.

Patient(s):

A total of 25 asymptomatic patients: 12 patients with DE (group 1) and 13 patients with ovarian endometriosis (group 2, control group).

Intervention(s):

Preoperative urodynamic evaluation.

Main Outcome Measure(s):

The impact of DE on urodynamic parameters.

Result(s):

For the first time, a urodynamic diagnosis of detrusor overactivity was correlated with the presence of deep infiltrating endometriosis (group 1, 91.7% [11/12] vs. group 2, 7.7% [1/13]). All involuntary detrusor contractions were detected only during the filling phase. All cystometry parameters were found to be altered in group 1 and statistically different between the two groups. No pressure/flow study parameter significantly differed between the two groups, besides maximal detrusor pressure (46 cmH2O [33–79] vs. 29 cmH2O [15–40]), which was significantly higher in group 1. Therefore, all detrusor-related parameters are statistically different between the two groups. Postvoid residual does not reach a statistically significant difference.

Conclusion(s):

DE could significantly impair detrusor functions. A preoperative urodynamic evaluation allows the attainment of important functional information, even in asymptomatic patients.

Read the full text at: http://www.fertstert.org/article/S0015-0282(13)00744-9/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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