Authors

John David Gordon, M.D., Michael DiMattina, M.D., Andrea Reh, M.D., Awie Botes, B.Sc., Gerard Celia, Ph.D., Mark Payson, M.D.

Volume 100, Issue 2, Pages 392-395, August 2013

Abstract

Objective:

To examine the utilization and outcomes of natural cycle (unstimulated) IVF as reported to the Society of Assisted Reproductive Technology (SART) in 2006 and 2007.

Design:

Retrospective analysis.

Setting:

Dataset analysis from the SART Clinical Outcome Reporting System national database.

Patient(s):

All patients undergoing IVF as reported to SART in 2006 and 2007.

Intervention(s):

None.

Main Outcome Measure(s):

Utilization of unstimulated IVF; description of patient demographics; and comparison of implantation and pregnancy rates between unstimulated and stimulated IVF cycles.

Result(s):

During 2006 and 2007 a total of 795 unstimulated IVF cycles were initiated. Success rates were age dependent, with patients <35 years of age demonstrating clinical pregnancy rates per cycle start, retrieval, and transfer of 19.2%, 26.8%, and 35.9%, respectively. Implantation rates were statistically higher for unstimulated compared with stimulated IVF in patients who were 35 to 42 years old. Conclusion(s):

Unstimulated IVF represents <1% of the total IVF cycles initiated in the United States. The pregnancy and live birth rates per initiated cycle were 19.2% and 15.2%, respectively, in patients <35 years old. The implantation rates in unstimulated IVF cycles compared favorably to stimulated IVF. Natural cycle IVF may be considered in a wide range of patients as an alternative therapy for the infertile couple.

Read the full text at: http://www.fertstert.org/article/S0015-0282(13)00453-6/fulltext