Hyperandrogenism during puberty in the development of polycystic ovary syndrome

Androgen secretion during pubertal development is a normal event. Polycystic ovary syndrome may be viewed as a maladaptation of this advantageous process.

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Authors

Shahla Nader, M.D.

Volume 100, Issue 1, Pages 39-42, July 2013

Abstract

The hormonal events of puberty, from adrenarche to menarche and beyond, include the secretion of androgens as well as estrogen and P. This normal pubertal process is briefly reviewed and a physiologic role for pubertal androgens proposed. It is further suggested that the hyperandrogenic state we call polycystic ovary syndrome is a maladaptation of the advantageous role of normal pubertal androgens.

Read the full text at: http://www.fertstert.org/article/S0015-0282(13)00414-7/fulltext


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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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