Parental attitudes toward fertility preservation in boys with cancer: context of different risk levels of infertility and success rates of fertility restoration

Parents of boys with cancer want some sort of fertility preservation, even if the risks of infertility or the success rates in restoring fertility were 20%.


Hooman Sadri-Ardekani, M.D., Ph.D., Mohammad-Mehdi Akhondi, Ph.D., Parvaneh Vossough, M.D., Haleh Maleki, M.Sc., Shirin Sedighnejad, B.Sc., Koorosh Kamali M.D., Ph.D., Behzad Ghorbani, M.D., Madelon van Wely, Ph.D., Fulco van der Veen, M.D., Ph.D., Sjoerd Repping, Ph.D.

Volume 99, Issue 3, Pages 796-802, 1 March 2013



To measure the parental attitudes towards fertility preservation in boys with cancer.


Retrospective cohort study.


Questionnaire survey via regular mail.


A total of 465-families whose sons were already treated for cancer.


The questionnaire was designed for two-groups based on age at the time of cancer diagnosis, i.e. children

Main Outcome Measure(s):

Descriptive statistics regarding a positive or negative attitude of parents towards fertility preservation options in context of different risk levels of infertility and success rates of fertility restoration.


The response rate was 78%. Sixty four percent of parents of boys ≥12 years would agree to store sperm obtained by masturbation and/or electro-ejaculation, while 54% of parents of boys

Conclusion (s):

All parents should be counseled about the risks of infertility due to cancer treatment, as many parents want to preserve their son’s fertility even if the risk of becoming infertile or the chances on fertility restoration are low.

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