The clinical utility of sperm DNA integrity testing: a guideline

This document describes the basics of sperm DNA integrity; assesses the evidence pertaining to the clinical utility of sperm DNA integrity testing; and targets areas that require more study.

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The Practice Committee of the American Society for Reproductive Medicine

Volume 99, Issue 3, Pages 673-677, 1 March 2013


Sperm DNA damage is more common in infertile men and may contribute to poor reproductive performance. However, current methods for assessing sperm DNA integrity do not reliably predict treatment outcomes and cannot be recommended routinely for clinical use.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.