Blastocyst culture and transfer in clinical-assisted reproduction: a committee opinion

Blastocyst embryo transfer improves the live-birth rate in good prognosis patients compared with cleavage-stage transfer. In unselected or poor prognosis patients, it is not proven superior to cleavage-stage transfer.

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The Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology

Volume 99, Issue 3, Pages 667-672, 1 March 2013


The purposes of this Practice Committee Opinion, which replaces the 2008 ASRM Practice Committee Opinion of the same name (Fertil Steril_ 2008;90:S174–7), are first, to review the literature regarding the clinical application of blastocyst transfer and second to identify the potential risks and laboratory issues related to use of this technology. This document does not apply to patients undergoing blastocyst culture and transfer for

preimplantation genetic testing/screening.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.