Low birth weight: Is it related to assisted reproductive technology or underlying infertility

We review the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.

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Authors

Laxmi A. Kondapalli, M.D., M.S.C.E., Alfredo Perales-Puchalt, M.D.

Volume 99, Issue 2, Pages 303-310, February 2013

Abstract

Since 1978, we have witnessed a successful evolution of assisted reproductive technology (ART), with improvement of the pregnancy rates and a growing demand. However, in recent years, there has been increasing concern regarding its safety due to the potential health impact on its infants. The raise of the developmental origins of adult disease 25 has positioned low birth weight (LBW) as a significant health issue. Despite multiple studies have associated ART with LBW, the etiology of this association remains largely unknown. This paper reviews the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)02544-7/fulltext


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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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