Reduced versus nonreduced twin pregnancies Obstetric performance in a cohort of interventional conceptions

The performance of twin pregnancies after fetal reduction procedure was tested in a prospective cohort study. Our work supports a lack of causative relationship between fetal reduction and pregnancy endpoint.

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Authors

Anat Hershko-Klement, M.D., Shlomo Lipitz, M.D., Amir Wiser, M.D., Arie Berkovitz, M.D.

Volume 99, Issue 1, Pages 163-167, January 2013

Abstract

Objective:

To describe the obstetrical performance of a selected population of twin pregnancies. Reduced versus non-reduced twin pregnancies were compared, after the successful completion of the 12th week.

Design:

A prospective cohort study. Setting: a single outpatient fertility center. Patients: a cohort of 464 twin pregnancies including both ovulation induction and ART pregnancies.

Interventions:

Fetal reduction procedure. Main outcome measures: pregnancy outcome, prematurity rate.

Results:

The study group included a cohort of 464 twin pregnancies in a single outpatient fertility center: 70 cases of twin pregnancies following a reduction procedure (15.1%) and 394 cases of non-reduced twins (84.9%). 8.6% of the non-reduced twin pregnancies went through an abortion as compared to 4.3% in the reduced group (P value=0.34). Mean age at delivery was also comparable between the two groups: 35.8 weeks in the reduced group and 35.6 weeks in the nonreduced group, and so was the rate of severe prematurity: 3.3% in the non-reduced group, 2.9% in the reduced group, P Value>0.5).

Conclusions:

Our work supports a lack of causative relationship between fetal reduction and pregnancy endpoint.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)02183-8/fulltext


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Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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