Authors

Michele Morelli, M.D., Ph.D., Rita Mocciaro, M.D., Roberta Venturella, M.D., Alberto Imperatore, M.D., Ph.D., Daniela Lico, M.D., Fulvio Zullo, M.D., Ph.D.

Vol 98, Issue 5, Pages 1336-1340.e1

Abstract

Objective:

To evaluate safety and efficacy, in terms of spillage risk and ovarian tissue-preservation, of mesial incision for laparoscopic dermoid cystectomy.

Design:

Randomized controlled trial.

Setting:

University

Patients:

Sixty-seven women with dermoid cysts.

Interventions:

Laparoscopic dermoid cystectomy performed by mesial incision (33 patients, study group) or antimesial incision (34 patients, control group).

Main outcomes:

Spillage of intracystic content rate, operative times, chemical peritonitis rate, intraoperative blood loss (Δ Hb) as primary outcomes. Post-operative ovarian reserve (Δ FSH levels, basal antral follicle number, mean ovarian diameter, peak systolic velocity at 3 and 12 months after surgery) as secondary outcome.

Results:

Spillage of intracystic content rate (P < 0.05) and operative time (P < 0.001) were significantly lower in study than in control group. None developed chemical peritonitis. ΔHb was higher in the study group, but not significantly. During the follow-up, median FSH values were significantly lower in the study group, with no differences in the E2 levels. Moreover, median basal antral follicle number, median ovarian diameter and median peak systolic velocity were significantly higher in the study group. Conclusions:

Ovarian mesial-side incision appears to be a safe and also tissue-sparing technique.

Clinical trial registration number:

NCT01590030

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)01848-1/fulltext