Do you need to definitively diagnose the location of a pregnancy of unknown location The case for yes

A definitive diagnosis should be made for PUL. Misclassification carries significant potential consequences. For nonviable PUL, presumptive diagnosis of EP without uterine curettage may be inaccurate.

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Authors

Lauren Rubal, M.D., Karine Chung, M.D., M.S.C.E.

Vol 98, Issue 5, Pages 1078-1084

Abstract

Pregnancy of unknown location (PUL) is a common diagnostic challenge. The primary diagnostic goal is to ensure that the PUL is non-viable prior to proceeding with any invasive procedures. In non-viable PUL, there are several diagnostic and treatment strategies, all of which are in general quite safe. However, the management option that provides the most definite diagnosis is uterine curettage. We advocate use of uterine curettage in all cases of non-viable PUL because it limits exposure to a chemotherapeutic agent to only those who need it and it allows for the most accurate information for counseling the patient on prognosis of future pregnancies.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)02252-2/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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