Authors

Enrico Carmina, M.D., Anna Maria Campagna, M.D., Pasquale Mansuet, M.D., Giustina Vitale, M.D., Daniel Kort, M.D., Roger Lobo, M.D.

Vol 98, Issue 4, Pages 1043-1046

Abstract

Objective:

To determine possible prediction of regular menses with aging in anovulatory women with PCOS.

Design:

Cohort.

Setting:

Academic practice.

Patients:

A total of 54 anovulatory women with PCOS and 28 age- and weight-matched controls.

Interventions:

Blood and ovarian ultrasound at baseline and after 5 years.

Major Outcome Measures:

Serum AMH, gonadotropins, androgens, insulin sensitivity, AMH, and ovarian ultrasound.

Results:

After 5 years, there was a significant decrease in AMH in women with PCOS and controls. (Ten of 54 anovulatory women became ovulatory after 5 yrs.) There was a significant negative correlation between baseline serum AMH and ovulatory function after 5 years. However, baseline serum AMH (< 4ng/ml) was associated with ovulatory function. Conclusion:

Serum AMH may help predict ovulatory function with aging in anovulatory women with PCOS.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)00652-8/fulltext