What is Endosalpingiosis

Endosalpingiosis appears to affect postmenopausal women at a rate much higher than previously reported. Endosalpingiosis and endometriosis occur concurrently in 34% of endosalpingiosis cases; however, the two diseases have different clinical presentations.

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Authors

Lucy R. Prentice, M.B.C.H.B., Alistair Stewart, B.Sc., Seema Mohiuddin, M.B.B.S., Neil P. Johnson, M.B.B.S.

Vol 98, Issue 4, Pages 942-947

Abstract

Objective:

To describe the demographics and clinical presentation of endosalpingiosis. To compare endosalpingiosis with endometriosis, particularly in regards to infertility and chronic pelvic pain.

Design:

Retrospective analysis.

Setting:

Hospital.

Patients:

We included women with a histologic diagnosis of endosalpingiosis, a second group with a histologic diagnosis of endometriosis, and a final group who had neither endosalpingiosis nor endometriosis, with histology reports after undergoing gynecologic surgery.

Interventions:

None.

Main Outcome measures:

Infertility and chronic pelvic pain.

Results:

We found that 34.5% of endosalpingiosis cases had concurrent endometriosis; 40% of the endosalpingiosis group were postmenopausal. Endometriosis was significantly associated with infertility (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.4–8.5) and chronic pelvic pain (OR 3.0, 95% CI 1.7–5.5). In contrast, there was no significant link between endosalpingiosis and infertility (OR 1.6, 95% CI 0.7–3.7) nor chronic pelvic pain (OR 0.8, 95% CI 0.5–1.5). Gynecologic malignancy occurred significantly more in premenopausal women with endosalpingiosis than in those without (OR 10.3, 95% CI 3.6–29.8).

Conclusions:

Endosalpingiosis appears to affect postmenopausal women at a rate much higher than previously reported. Endosalpingiosis and endometriosis occur concurrently in 34% of endosalpingiosis cases, however the two diseases have different clinical presentations. This demonstrates that endosalpingiosis is not a variant of endometriosis.

Read the full text at: http://www.fertstert.org/article/S0015-0282(12)00692-9/fulltext


Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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